Evidence map›Paper›PMID 39295728›Full record

ArticleCureus2024

Parathyroid Cyst and Micropapillary Thyroid Carcinoma: A Case Study of Unexpected Concurrent Endocrine Pathologies.

Tammy Luan, Madison Guido, Elizabeth Whittington, Deanna Jantsch, Adam D Kurtin

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tammy LuanDepartment of Surgery, University of Miami JFK Hospital, Atlantis, USA.
Madison GuidoDepartment of Surgery, University of Miami Miller School of Medicine, Miami, USA.
Elizabeth WhittingtonDepartment of Pathology and Laboratory, HCA Florida St. Lucie Hospital, Port St. Lucie, USA.
Deanna JantschDepartment of Surgery, HCA Florida St. Lucie Hospital, Port St. Lucie, USA.
Adam D KurtinDepartment of Surgery, HCA Florida St. Lucie Hospital, Port St. Lucie, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid cysts (PCs) are rare tumors that predominantly affect middle-aged women and are characterized by symptoms of hyperparathyroidism, including fatigue, bone pain, and gastrointestinal issues. Management typically involves surgical resection due to their potential to cause profound hyperparathyroidism and hypercalcemia. PCs occasionally coexist with thyroid malignancies, including micropapillary thyroid carcinoma (MPTC), although the pathophysiological link between PCs and thyroid cancers remains unclear. We present a case of a 62-year-old woman with symptomatic hypercalcemia and a large cystic mass adjacent to the left inferior thyroid pole, initially suspected to be a PC. Preoperative imaging, including an ultrasound (US) and sestamibi scan, guided surgical intervention, resulting in en bloc resection of the PC along with a left hemithyroidectomy. Pathological examination confirmed the presence of both a PC and MPTC, raising the question as to whether there is a possible correlation between primary hyperparathyroidism (PHPT) and thyroid malignancy. This report aims to highlight the current PC management protocol, underscore the importance of thorough diagnostic evaluation and surgical strategies in addressing concurrent parathyroid and thyroid pathologies, and explore potential pathophysiological connections between these conditions.

Indexed as

acute hypercalcemiahypercalcemic primary hyperparathyroidismmicropapillary thyroid carcinomapapillary thyroid carcinomaparathyroid adenomaparathyroid cystparathyroidectomyparathyroid tumorprimary hyperparathyroidismthyroidectomy

Identifiers

PMID39295728
PMCPMC11410449

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.