Evidence map›Paper›PMID 39295427›Full record

Trial reportClinical and experimental dental research2024

Effect of Needle Insertion Angle on Pain During Labial Infiltration Anesthesia of the Anterior Maxilla: A Randomized Clinical Trial.

Amirhossein Moaddabi, Tahereh Molania, Alireza Arezoumandi, Sahar Ghaedsharaf, Mariangela Cernera, Roya Nikbakht, Parisa Soltani, Gianrico Spagnuolo, Shirin Shahnaseri

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical and experimental dental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amirhossein MoaddabiDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Dental Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Tahereh MolaniaDepartment of Oral Medicine, Dental Research Center, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
Alireza ArezoumandiStudents Research Committee, School of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
Sahar GhaedsharafPrivate Practice, Tehran, Iran.
Mariangela CerneraDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy.ORCID 0000-0001-6356-6536
Roya NikbakhtDepartment of Biostatistics and Epidemiology, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Parisa SoltaniDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy.ORCID 0000-0002-9273-5279
Gianrico SpagnuoloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Naples, Italy.ORCID 0000-0003-3769-9786
Shirin ShahnaseriDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Meharry Medical College, Nashville, Tennesse, USA.

Funding

This work was financially supported by Mazandaran University of Medical Sciences (#9621).
6 · The paper itself

Abstract

objectivesThis study aimed to assess the effect of needle insertion angle on pain during labial infiltration anesthesia in the anterior maxillary region. MATERIAL AND

methodsIn this parallel-design randomized clinical trial, participants were randomly assigned to four groups for labial infiltration anesthesia of the anterior maxilla. Local anesthesia was performed with needle orientation parallel to the longitudinal axis of the tooth using a conventional syringe (Syringe-0), needle at α angle with a conventional syringe (Syringe-α), computer-controlled local anesthetic delivery (CCLAD) device parallel to the longitudinal axis of the tooth (CCLAD-0), and CCLAD at α angle (CCLAD-α). The heart rate (HR), blood pressure (BP), and respiratory rate (RR) of participants were measured before needle insertion, immediately after needle insertion, and immediately after the injection by a vital signs monitor. The level of pain experienced by participants was quantified using a numerical rating scale (NRS). Data were analyzed by repeated-measures ANOVA and regression models (α = 0.05).

resultsThirty-six participants aged from 21 to 60 years, with a mean age of 35.36 years were recruited. The mean pain scores were 7.44, 4.67, 2.89, and 0.67 in groups Syringe-0, Syringe-α, CCLAD-0, and CCLAD-α, respectively (p < 0.001). Age and sex had no significant effect on pain scores (p = 0.914 and p = 0.702, respectively). The four groups had no significant difference in vital signs (p > 0.05).

conclusionsInjection at an α angle and the application of CCLAD can be used in clinical practice to decrease the pain experienced by participants during labial infiltration anesthesia of the anterior maxilla.

trial registrationIranian Registry of Clinical Trials: IRCT20230719058849N1.

Indexed as

Anesthesia, DentalAnesthesia, LocalAnesthetics, LocalMaxillaNeedlesPain MeasurementAdultFemaleHumansMaleMiddle AgedYoung AdultAnesthetics, Localanesthesia, localmaxillaneedlespain

Identifiers

PMID39295427
PMCPMC11411153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.