Evidence map›Paper›PMID 39295298›Full record

ReviewYeast (Chichester, England)2024

Exploring Saccharomycotina Yeast Ecology Through an Ecological Ontology Framework.

Marie-Claire Harrison, Dana A Opulente, John F Wolters, Xing-Xing Shen, Xiaofan Zhou, Marizeth Groenewald, Chris Todd Hittinger, Antonis Rokas, Abigail Leavitt LaBella

Abstract readReview
In one paragraph

Review in Yeast (Chichester, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Macroevolution of Filamentation Morphology Across thebioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marie-Claire HarrisonDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.
Dana A OpulenteDepartment of Biology, Villanova University, Villanova, Pennsylvania, USA.
John F WoltersLaboratory of Genetics, DOE Great Lakes Bioenergy Research Center, Center for Genomic Science Innovation, Wisconsin Energy Institute, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Xing-Xing ShenCentre for Evolutionary and Organismal Biology, Institute of Insect Sciences, Zhejiang University, Hangzhou, China.
Xiaofan ZhouGuangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Center, South China Agricultural University, Guangzhou, China.
Marizeth GroenewaldWesterdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
Chris Todd HittingerLaboratory of Genetics, DOE Great Lakes Bioenergy Research Center, Center for Genomic Science Innovation, Wisconsin Energy Institute, J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-5088-7461
Antonis RokasDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.
Abigail Leavitt LaBellaDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis, North Carolina, USA.ORCID 0000-0003-0068-6703

Funding

Deciphering the phenotypic and genomic traits that underlie the evolution of pathogenicity differences among Aspergillus fumigatus and its close relativesR01AI153356 · NIAID · VANDERBILT UNIVERSITY · PI Antonis Rokas · 2022 to 2026
$3.5M
NIAID NIH HHS R01 AI153356This work was supported by the NSF for Distinguished Young Scholars of Zhejiang Province (LR23C140001), Key Research Project of Zhejiang Lab (2021PE0AC04), National Institute of Allergy and Infectious Diseases (R01 AI153356), National Institute of Food and Agriculture Hatch Project (7005101), Burroughs Wellcome Fund, Directorate for Biological Sciences (DEB-2110403, DEB-2110404), Office of the Vice Chancellor for Research and Graduate Education with funding from the Wisconsin Alumni Research Foundation H.I. Romnes Faculty Fellowship, and DOE Great Lakes Bioenergy Research Center (DOE BER Office of Science DE-SC0018409).
6 · The paper itself

Abstract

Yeasts in the subphylum Saccharomycotina are found across the globe in disparate ecosystems. A major aim of yeast research is to understand the diversity and evolution of ecological traits, such as carbon metabolic breadth, insect association, and cactophily. This includes studying aspects of ecological traits like genetic architecture or association with other phenotypic traits. Genomic resources in the Saccharomycotina have grown rapidly. Ecological data, however, are still limited for many species, especially those only known from species descriptions where usually only a limited number of strains are studied. Moreover, ecological information is recorded in natural language format limiting high throughput computational analysis. To address these limitations, we developed an ontological framework for the analysis of yeast ecology. A total of 1,088 yeast strains were added to the Ontology of Yeast Environments (OYE) and analyzed in a machine-learning framework to connect genotype to ecology. This framework is flexible and can be extended to additional isolates, species, or environmental sequencing data. Widespread adoption of OYE would greatly aid the study of macroecology in the Saccharomycotina subphylum.

Indexed as

EcosystemAscomycotaEcologyGenome, FungalGenotypeMachine Learningcontrolled vocabularydynamicformalisolation environmentmacroecologystatistical enrichment

Identifiers

PMID39295298
PMCPMC11522959

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.