Evidence map›Paper›PMID 39294888›Full record

ArticleVeterinary medicine and science2024

Ultrasound-assisted minimally invasive technique for tissue collection from bovine mammary glands.

Alysia L Vang, Waneska S Frizzarini, Haylee H Webster, Thiago O Cunha, Kathryn M Nelson, Joao R R Dorea, Laura L Hernandez

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Animals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alysia L VangDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4790-8924
Waneska S FrizzariniDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-7901-4004
Haylee H WebsterDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-0945-2727
Thiago O CunhaDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4356-8651
Kathryn M NelsonDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Joao R R DoreaDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9849-7358
Laura L HernandezDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-7591-5203

Funding

Training & Education to Advance Minorities in Science (TEAM-Science)R25GM083252 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2008 to 2021
$8.5M
Biotechnology Training ProgramT32GM135066 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCOTT M. COYLE, BRIAN G FOX · 2020 to 2026
$7.0M
National Institute of Food and Agriculture of the United States Department of Agriculture 2020-67015-30831National Institute of Food and Agriculture of the United States Department of Agriculture WIS04094National Institute of Health Training R25GM083252National Institute of Health Training T32GM135066NIGMS NIH HHS R25 GM083252NIGMS NIH HHS T32 GM135066
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe objective of this case report was to describe an ultrasound-guided, minimally invasive method for longitudinal mammary gland tissue collection from the bovine species. MATERIALS AND

methodsBiopsies were performed on 14 8-week-old calves and 113 10-week-old calves. A subset of 36 animals had repeated mammary gland biopsies through the first lactation. Mammary gland biopsies were performed using a disposable biopsy punch. The technique was also performed on multiparous cows on other independent research trials.

resultsOne-hundred and thirteen animals healed from the 10-week biopsies with no complications. Of the 36 animals that received repeated biopsies, one developed mastitis due to premature suture removal and one had recurring mastitis in all quarters. Thirty-three animals underwent all biopsies during gestation. Thirty of the original 36 are currently in lactation and still undergoing repeated biopsies. The method has also been successfully replicated on multiparous cows in separate studies. DISCUSSION AND

conclusionThe described technique is a safe, reliable method for cattle mammary gland biopsies beginning at eight weeks of age and can be utilized to obtain repeated tissue collection from individual animals. The technique is also straightforward to perform and utilizes simple tools while providing acceptable amounts of tissue for most applications, with low risk for infection and long-term tissue damage.

Indexed as

Mammary Glands, AnimalAnimalsBiopsyCattleFemaleTissue and Organ HarvestingUltrasonography, Interventionalbiopsybovinelongitudinalmammary gland

Identifiers

PMID39294888
PMCPMC11410675

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.