Evidence map›Paper›PMID 39294268›Full record

ArticleScientific reports2024

3D-printed porous titanium rods equipped with vancomycin-loaded hydrogels and polycaprolactone membranes for intelligent antibacterial drug release.

Zheru Ma, Yao Zhao, Zhe Xu, Yao Zhang, Yu Han, Haozhuo Jiang, Peng Sun, Wei Feng

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Zheru Ma *Department of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Yao Zhao *Department of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Zhe Xu *Department of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Yao Zhang *Department of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Yu HanDepartment of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Haozhuo JiangDepartment of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Peng SunDepartment of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China.
Wei FengDepartment of Bone and Joint Surgery, Orthopedic Center, The First Hospital of Jilin University, 72 Xinmin Street, Changchun, 130021, Jilin, China. feng_wei@jlu.edu.cn.

Funding

the Jilin Provincial Science and Technology Department Project No. 20240302070GX
6 · The paper itself

Abstract

Implant-related infections pose significant challenges to orthopedic surgeries due to the high risk of severe complications. The widespread use of bioactive prostheses in joint replacements, featuring roughened surfaces and tight integration with the bone marrow cavity, has facilitated bacterial proliferation and complicated treatment. Developing antibacterial coatings for orthopedic implants has been a key research focus in recent years to address this critical issue. Researchers have designed coatings using various materials and antibacterial strategies. In this study, we fabricated 3D-printed porous titanium rods, incorporated vancomycin-loaded mPEG

Indexed as

Anti-Bacterial AgentsHydrogelsPolyestersPrinting, Three-DimensionalTitaniumVancomycinAnimalsBiofilmsCoated Materials, BiocompatibleDrug Delivery SystemsDrug LiberationPolyethylene GlycolsPorosityRabbitsStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsCoated Materials, BiocompatibleHydrogelspolycaprolactonePolyestersPolyethylene GlycolsTitaniumVancomycin3D printingInfectionPCLPEGTitaniumVancomycin

Identifiers

PMID39294268
PMCPMC11411058

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.