Evidence map›Paper›PMID 39294243›Full record

ArticlePediatric research2025

Mediative role of body mass index in cardiorespiratory fitness-associated vascular remodeling in youth.

Luisa Semmler, Lisa Baumgartner, Heidi Weberruß, Raphael Pirzer, Renate Oberhoffer-Fritz

Abstract read
In one paragraph

Article in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luisa SemmlerDepartment of Neurology, Klinikum rechts der Isar, Technical University Munich, Munich, Germany. luisa.semmler@tum.de.
Lisa BaumgartnerInstitute of Preventive Pediatrics, Technical University of Munich, Munich, Germany.
Heidi WeberrußClinic for Pediatric and Adolescent Medicine, Klinikum Bayreuth, Bayreuth, Germany.
Raphael PirzerDepartment of Anaesthesiology and Operative Intensive Care, University Hospital Augsburg, Augsburg, Germany.
Renate Oberhoffer-FritzInstitute of Preventive Pediatrics, Technical University of Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundData on fitness-associated arterial remodeling in children is limited. We assessed the relation between cardiorespiratory fitness (CRF) and intima-media thickness (IMT), diameter, IMT:diameter-ratio (IDR), and tensile stress of the common carotid artery (CCA) in 697 healthy German schoolchildren. Further, we explored how body mass index (BMI) may influence these associations.

methodsWe measured the vascular parameters with a high-resolution ultrasound device. We determined CRF using the FITNESSGRAM® PACER test and calculated each child's allometrically scaled peak oxygen uptake capacity (VO

resultsVO

conclusionCRF appears to be linked to uniform arterial remodeling with balanced hemodynamics and to further alleviate BMI-associated, potentially adverse vascular alterations, highlighting its significant role in cardiovascular health in youth. IMPACT: Data on CRF-associated arterial remodeling in youth is limited. Higher VO

Indexed as

Body Mass IndexCardiorespiratory FitnessVascular RemodelingAdolescentCarotid Artery, CommonCarotid Intima-Media ThicknessChildFemaleGermanyHumansMaleOxygen Consumption

Identifiers

PMID39294243
PMCPMC12122364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.