Evidence map›Paper›PMID 39293984›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Aggregatibacter aphrophilus-associated Sphenoid Sinusitis Causing Orbital Cellulitis, Meningitis, and Venous Sinus Thrombosis.

Nobuhiko Ohashi, Yoshino Kawamura, Shota Kamijima, Rie Watanabe, Shintaro Yamazaki, Nodoka Matsushima, Ko-Ichi Tazawa

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nobuhiko OhashiDepartment of Neurology, Nagano Red Cross Hospital, Japan.
Yoshino KawamuraDepartment of Neurology, Nagano Red Cross Hospital, Japan.
Shota KamijimaDepartment of Neurology, Nagano Red Cross Hospital, Japan.
Rie WatanabeDepartment of Neurology, Nagano Red Cross Hospital, Japan.
Shintaro YamazakiDepartment of Otorhinolaryngology, Nagano Red Cross Hospital, Japan.
Nodoka MatsushimaDepartment of Clinical Laboratory, Nagano Red Cross Hospital, Japan.
Ko-Ichi TazawaDepartment of Neurology, Nagano Red Cross Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report an 81-year-old woman with no significant medical history who developed a fever, headache, and right eyelid swelling. Magnetic resonance imaging (MRI) showed eye proptosis, sphenoid opacity, enlarged cavernous sinus, and dilated right superior ophthalmic vein (SOV). Subsequent enhanced MRI revealed intraventricular debris and thrombosis in the right SOV and the left transverse and sigmoid sinuses. Blood cultures were positive for Aggregatibacter aphrophilus, as identified by mass spectrometry. The patient responded well to antibiotics, anticoagulants, and surgical drainage of sphenoid sinusitis. To our knowledge, this is the first case of A. aphrophilus sphenoid sinusitis causing orbital cellulitis, meningitis, and venous sinus thrombosis.

Indexed as

Aggregatibacter aphrophilusMeningitisMeningitis, BacterialOrbital CellulitisPasteurellaceae InfectionsSinus Thrombosis, IntracranialSphenoid SinusitisAged, 80 and overAnti-Bacterial AgentsFemaleHumansMagnetic Resonance ImagingAnti-Bacterial AgentsAggregatibacter aphrophilusmass spectrometrymeningitisorbital cellulitissphenoid sinusitisvenous sinus thrombosis

Identifiers

PMID39293984
PMCPMC12120218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.