Evidence map›Paper›PMID 39293715›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2024

Impact of metabolic and weight components on incident asthma using a real-world cohort.

Melissa H Bloodworth, Patrick J Staso, Shi Huang, Eric Farber-Eger, Kevin D Niswender, Frank E Harrell, Quinn S Wells, Leonard B Bacharier, Megan M Shuey, Katherine N Cahill

Abstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Ovarian hormones and obesity drive Th17-mediated airway inflammation through estrogen receptor-α signaling.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  4. Article
  5. Association of daily steps over time with adult asthma incidence.The Journal of allergy and clinical immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melissa H BloodworthDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Patrick J StasoDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Shi HuangDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Eric Farber-EgerDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Kevin D NiswenderDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Frank E HarrellDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Quinn S WellsDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.
Leonard B BacharierDepartment of Pediatrics, Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, Tennessee.
Megan M ShueyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Katherine N CahillDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: katherine.cahill@vumc.org.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Building Interdisciplinary Research Careers in Women's HealthK12HD043483 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARTMANN, KATHERINE E, MAJOR, AMY S · 2002 to 2023
$10.3M
Glucagon-Like Peptide-1 Receptor Agonist Treatment in Adult, Obesity-Related, Symptomatic AsthmaU01AI155299 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL, CAHILL, KATHERINE N · 2021 to 2025
$8.6M
Interdisciplinary Training in Rheumatic DiseasesT32AR059039 · NIAMS · VANDERBILT UNIVERSITY · PI Tracy Minan Frech, AMY S MAJOR · 2010 to 2026
$4.3M
GLP-1R agonist immune targets in lean and obesity-associated asthmaR01AI182159 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Katherine N Cahill · 2024 to 2026
$2.6M
Automated Storage and Retrieval of Biological SystemsS10RR025141 · NCRR · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2008 to 2008
$988k
THE ROLE OF PROSTAGLANDIN D2 IN THE RESPIRATORY SYMPTOMS OF ASPIRIN EXACERBATED RESPIRATORY DISEASEK23AI118804 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CAHILL, KATHERINE N · 2015 to 2019
$951k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS S10 RR025141NIAID NIH HHS K23 AI118804NIAID NIH HHS R01 AI182159NIAID NIH HHS U01 AI155299NIAMS NIH HHS T32 AR059039NICHD NIH HHS K12 HD043483
6 · The paper itself

Abstract

backgroundObesity and metabolic dysregulation (MetD) have increasing prevalence and adversely affect asthma morbidity and therapeutic response.

objectiveTo determine the role of weight and MetD on incident asthma in adulthood.

methodsIn a retrospective, longitudinal cohort of patients, we performed a time-to-asthma diagnosis analysis after a 3-year landmark period (t

resultsIn total, 90,081 patients met the inclusion criteria, with 836 cases (0.93%) of incident asthma in our primary cohort. Diabetes present at t

conclusionWeight and diabetes prevention and management represent modifiable risk factors for adult asthma development.

Indexed as

AsthmaObesityAdultAgedBody WeightDiabetes MellitusFemaleGlycated HemoglobinHumansIncidenceLongitudinal StudiesMaleMiddle AgedRetrospective StudiesRisk FactorsGlycated Hemoglobin

Identifiers

PMID39293715
PMCPMC11812921

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.