Evidence map›Paper›PMID 39292985›Full record

ArticleNeurology2024

Association of Adherence to a MIND-Style Diet With the Risk of Cognitive Impairment and Decline in the REGARDS Cohort.

Russell P Sawyer, Jessica Blair, Rhonna Shatz, Jennifer J Manly, Suzanne E Judd

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In one paragraph

Article in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Diets to promote healthy brain ageing.Nature reviews. Neurology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Russell P SawyerFrom the Department of Neurology and Rehabilitation Medicine (R.P.S., R.S.), University of Cincinnati College of Medicine, OH; Biostatistics Department (J.B., S.E.J.), School of Public Health, University of Alabama at Birmingham; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M.), G.H. Sergievsky Center (J.J.M.), and Department of Neurology (J.J.M.), Vagelos College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York.ORCID 0000-0003-2426-1929
Jessica BlairFrom the Department of Neurology and Rehabilitation Medicine (R.P.S., R.S.), University of Cincinnati College of Medicine, OH; Biostatistics Department (J.B., S.E.J.), School of Public Health, University of Alabama at Birmingham; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M.), G.H. Sergievsky Center (J.J.M.), and Department of Neurology (J.J.M.), Vagelos College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York.ORCID 0000-0002-5842-6827
Rhonna ShatzFrom the Department of Neurology and Rehabilitation Medicine (R.P.S., R.S.), University of Cincinnati College of Medicine, OH; Biostatistics Department (J.B., S.E.J.), School of Public Health, University of Alabama at Birmingham; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M.), G.H. Sergievsky Center (J.J.M.), and Department of Neurology (J.J.M.), Vagelos College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York.
Jennifer J ManlyFrom the Department of Neurology and Rehabilitation Medicine (R.P.S., R.S.), University of Cincinnati College of Medicine, OH; Biostatistics Department (J.B., S.E.J.), School of Public Health, University of Alabama at Birmingham; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M.), G.H. Sergievsky Center (J.J.M.), and Department of Neurology (J.J.M.), Vagelos College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York.ORCID 0000-0002-9481-7497
Suzanne E JuddFrom the Department of Neurology and Rehabilitation Medicine (R.P.S., R.S.), University of Cincinnati College of Medicine, OH; Biostatistics Department (J.B., S.E.J.), School of Public Health, University of Alabama at Birmingham; Taub Institute for Research on Alzheimer's Disease and the Aging Brain (J.J.M.), G.H. Sergievsky Center (J.J.M.), and Department of Neurology (J.J.M.), Vagelos College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital, New York.ORCID 0000-0001-7594-6587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesDiet may influence the development of cognitive impairment and affect cognitive decline, but whether this relationship varies between Black American and White American people is unclear. This study examined the association of Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) and incident cognitive impairment and cognitive trajectories in a biracial prospective cohort study.

methodsUsing data derived from the Food Frequency Questionnaire in the REasons for Geographic and Racial Differences in Stroke study, we compared MIND diet adherence with incident cognitive impairment and cognitive trajectory in Black participants and White participants. Logistic regression was used to model MIND diet score (continuous variable and using tertiles) and incident cognitive impairment after adjusting for age, sex, race, region, education, income, total energy, hypertension history, dyslipidemia, diabetes, estimated glomerular filtration rate, ischemic heart conditions, atrial fibrillation, and lifestyle factors including sedentary, obesity, and smoking. Mixed-effects models were used to examine the association between cognitive trajectory and MIND diet adherence.

resultsDietary data to calculate the MIND diet score and cognitive data were available on 14,145 participants with a mean age of 64 years (SD 9.0 years) that was 56.7% female. Greater MIND diet adherence was associated with a decreased incidence of cognitive impairment (odds ratio [OR] 0.96, 95% CI 0.93-0.99, DISCUSSION: Greater MIND diet adherence was associated with decreased risk of cognitive impairment in female participants but not male participants, with no difference between Black participants and White participants. However, MIND diet adherence was a better predictor of cognitive trajectory in Black participants than in White participants.

Indexed as

Dietary Approaches To Stop HypertensionAgedBlack or African AmericanCognition DisordersCognitive DysfunctionCohort StudiesDiet, MediterraneanFemaleHumansIncidenceMaleMiddle AgedPatient ComplianceProspective StudiesRisk FactorsWhite

Identifiers

PMID39292985
PMCPMC11413742

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.