Evidence map›Paper›PMID 39292753›Full record

ArticleEpigenetics2024

Maternal glucose levels and late pregnancy circulating extracellular vesicle and particle miRNAs in the MADRES pregnancy cohort.

Elizabeth C Anderson, Helen B Foley, Joshua J Levy, Megan E Romano, Jiang Gui, Jessica L Bentz, Luis E Maldonado, Shohreh F Farzan, Theresa M Bastain, Carmen J Marsit and 2 more

Abstract read
In one paragraph

Article in Epigenetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elizabeth C AndersonDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.ORCID 0000-0002-1050-5470
Helen B FoleyDivision of Environmental Health, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Joshua J LevyEmerging Diagnostic and Investigative Technologies, Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
Megan E RomanoDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Jiang GuiDepartment of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Jessica L BentzDepartment of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Luis E MaldonadoDivision of Environmental Health, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Shohreh F FarzanDivision of Environmental Health, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Theresa M BastainDivision of Environmental Health, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Carmen J MarsitGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Carrie V BretonDivision of Environmental Health, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Caitlin G HoweDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4M
Project 3: Maternal Exposure to Environmental Hazards and Psychosocial Stressors and Postpartum Allostatic LoadP50MD015705 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN · 2020 to 2024
$8.1M
Project 2: Environmental Exposures, Stress, and Maternal Pregnancy-Related Weight OutcomesP50ES026086 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M · 2015 to 2019
$3.7M
Influence of prenatal psychosocial stressors on maternal and fetal circulating miRNAsR01MD011698 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN, MARSIT, CARMEN JOSEPH · 2017 to 2021
$3.3M
MicroRNA, Environmental Exposures and Newborn OutcomesR01ES025145 · NIEHS · EMORY UNIVERSITY · PI KOESTLER, DEVIN CHARLES, MARSIT, CARMEN JOSEPH · 2016 to 2019
$1.8M
Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAsR00ES030400 · NIEHS · DARTMOUTH COLLEGE · PI HOWE, CAITLIN GRACE · 2020 to 2022
$726k
NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P50 ES026086NIEHS NIH HHS R00 ES030400NIEHS NIH HHS R01 ES025145NIH HHS UH3 OD023287NIMHD NIH HHS P50 MD015705NIMHD NIH HHS R01 MD011698Wellcome Trust
6 · The paper itself

Abstract

Maternal hyperglycemia during pregnancy adversely affects maternal and child outcomes. While mechanisms are not fully understood, maternal circulating miRNAs may play a role. We examined whether continuous glucose levels and hyperglycemia subtypes (gestational diabetes, type 2 diabetes, and glucose intolerance) were associated with circulating miRNAs during late pregnancy. Seven miRNAs (hsa-miR-107, hsa-let-7b-5p, hsa-miR-126-3p, hsa-miR-181a-5p, hsa-miR-374a-5p, hsa-miR-382-5p, and hsa-miR-337-5p) were associated (

Indexed as

Diabetes, GestationalExtracellular VesiclesAdultBlood GlucoseCirculating MicroRNACohort StudiesDiabetes Mellitus, Type 2FemaleGlucose IntoleranceHumansHyperglycemiaMicroRNAsPregnancyBlood GlucoseCirculating MicroRNAMicroRNAsdiabetesglucosemiRNApregnancy

Identifiers

PMID39292753
PMCPMC11734885

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.