Evidence map›Paper›PMID 39292751›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Actomyosin contraction in the follicular epithelium provides the major mechanical force for follicle rupture during

Stella E Cho, Wei Li, Andrew M Beard, Jonathan A Jackson, Risa Kiernan, Kazunori Hoshino, Adam C Martin, Jianjun Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stella E ChoDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.
Wei LiDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.
Andrew M BeardDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.
Jonathan A JacksonDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0001-5051-1499
Risa KiernanDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.
Kazunori HoshinoDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.ORCID 0000-0002-7080-7825
Adam C MartinDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0001-8060-2607
Jianjun SunDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269.ORCID 0000-0002-6015-738X

Funding

MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6M
Tissue morphogenesis: From signals to forcesR35GM144115 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Adam Christopher Martin · 2022 to 2026
$3.0M
Genetic interrogation of conserved follicular factors for matrix metalloproteinase regulation and ovulationR01HD086175 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, JIANJUN · 2016 to 2020
$1.7M
Physiological Functions of Female Reproductive Tract SecretionsR01HD097206 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, JIANJUN · 2020 to 2025
$1.6M
Leica TCS SP8 FSU AOBS 405 UV Spectral Confocal MicroscopeS10OD016435 · OD · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2014 to 2014
$456k
HHS | NIH (NIH) R01-HD086175HHS | NIH (NIH) R01-HD097206HHS | NIH (NIH) R35-GM144115NICHD NIH HHS R01 HD086175NICHD NIH HHS R01 HD097206NIGMS NIH HHS R35 GM144115NIGMS NIH HHS T32 GM008313NIH HHS S10 OD016435NSF (NSF) 2223957
6 · The paper itself

Abstract

Ovulation is critical for sexual reproduction and consists of the process of liberating fertilizable oocytes from their somatic follicle capsules, also known as follicle rupture. The mechanical force for oocyte expulsion is largely unknown in many species. Our previous work demonstrated that

Indexed as

ActomyosinDrosophila ProteinsOctopamineOvarian FollicleOvulationActinsAnimalsDrosophilaDrosophila melanogasterEpitheliumFemaleMyosin Type IIOocytesrho GTP-Binding ProteinsActinsActomyosinDrosophila ProteinsMyosin Type IIOctopamineRho1 protein, Drosophilarho GTP-Binding Proteinsactomyosin contractionfollicle rupturemechanical forceovulationRho1

Identifiers

PMID39292751
PMCPMC11441566

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.