Evidence map›Paper›PMID 39292750›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Measurement of adhesion and traction of cells at high yield reveals an energetic ratchet operating during nephron condensation.

Jiageng Liu, Louis S Prahl, Aria Zheyuan Huang, Alex J Hughes

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jiageng LiuDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-7936-3669
Louis S PrahlDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Aria Zheyuan HuangDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0009-0009-3042-3171
Alex J HughesDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0001-6801-3455

Funding

A developmental engineering toolbox for large-scale tissue engineeringR35GM133380 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Alex Hughes · 2019 to 2026
$3.3M
Engineering induction and assembly of human kidney tissueR01DK132296 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI HUGHES, ALEX · 2022 to 2025
$1.8M
Synthetic approaches to study cell polarity related kidney defectsF32DK126385 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI PRAHL, LOUIS SKJEI · 2020 to 2023
$209k
HHS | NIH (NIH) NIDDK R01DK132296HHS | NIH (NIH) NIGMS MIRA R35GM133380NIDDK NIH HHS F32 DK126385NIDDK NIH HHS R01 DK132296NIGMS NIH HHS R35 GM133380NSF (NSF) CAREER award 2047271NSF (NSF) MRSEC DMR-2309043NSF (NSF) NNCI-2025608NSF | NSF Graduate Research Fellowship Program (GRFP) 2023356502
6 · The paper itself

Abstract

Developmental biology-inspired strategies for tissue-building have extraordinary promise for regenerative medicine, spurring interest in the relationship between cell biophysical properties and morphological transitions. However, mapping gene or protein expression data to cell biophysical properties to physical morphogenesis remains challenging with current techniques. Here, we present

Indexed as

Cell AdhesionNephronsAnimalsCell DifferentiationDogsMadin Darby Canine Kidney CellsMiceSignal Transductionbioengineeringcell sortingkidney developmentmorphogenesis

Identifiers

PMID39292750
PMCPMC11441508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.