Evidence map›Paper›PMID 39292653›Full record

ArticlePLOS global public health2024

Projected impact of fast-tracking of anti-retroviral treatment coverage on vertical transmission of HIV in India.

Pradeep Kumar, Chinmoyee Das, Subrata Biswas, Nidhi Priyam, Lalit Singh Kharayat, Damodar Sahu, Sanjay K Rai, Sheela V Godbole, Elangovan Arumugam, P V M Lakshmi and 6 more

Abstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pradeep KumarNational AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.ORCID https://orcid.org/0000-0002-7638-1263
Chinmoyee DasNational AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.
Subrata BiswasNational AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.
Nidhi PriyamNational AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.ORCID https://orcid.org/0009-0006-0209-6829
Lalit Singh KharayatNational AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.
Damodar SahuIndian Council of Medical Research, National Institute of Medical Statistics, New Delhi, India.
Sanjay K RaiAll India Institute of Medical Sciences, New Delhi, India.
Sheela V GodboleIndian Council of Medical Research, National AIDS Research Institute, Pune, India.
Elangovan ArumugamIndian Council of Medical Research, National Institute of Epidemiology, Chennai, India.ORCID https://orcid.org/0000-0003-4491-7171
P V M LakshmiPostgraduate Institute of Medical Education and Research, Chandigarh, India.
Shanta DuttaIndian Council of Medical Research, National Institute of Cholera and Enteric Diseases, Kolkata, India.
H Sanayaima DeviRegional Institute of Medical Sciences, Imphal, India.
Arvind PandeyIndian Council of Medical Research, National Institute of Medical Statistics, New Delhi, India.
Dandu Chandra Sekhar ReddyInstitute of Medical Sciences, Banaras Hindu University, Varanasi, India.ORCID https://orcid.org/0000-0003-2397-9971
Sanjay MehendaleIndian Council of Medical Research, New Delhi, India.
Shobini RajanNational AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.ORCID https://orcid.org/0000-0001-6109-538X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the five high-level goals under Phase V of the National AIDS and STD Control Programme (NACP) of the Government of India is the elimination of vertical transmission of HIV. In this paper, we estimate the potential impact of maintaining and enhancing the anti-retroviral treatment under the NACP in terms of averting new infections and vertical transmission rates vis-à-vis no intervention scenario. We used India's HIV Estimates 2022 models to create treatment coverage scenarios of no interventions, status quo, business as usual, on-track and fast-track scenarios from 2023 to 2030. Our analysis indicates that fast-tracking scale-up of treatment services would avert almost 41000 child infections from 2023 to 2030 leading to a vertical transmission rate of around 7.70% in 2030 vis-a-vis no interventions scenario. Higher and sustained ART coverage would not only take the country closer to the elimination goals but would also prevent thousands of vertical transmissions, thus bringing a lot of benefits to HIV-positive pregnant women and their families. Supported by efforts for the prevention of new infections in the general population, India is on track for the attainment of elimination of vertical transmission of HIV by 2030.

Identifiers

PMID39292653
PMCPMC11410226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.