Evidence map›Paper›PMID 39292467›Full record

ArticleTranslational vision science & technology2024

Peripheral Superficial Retina Vascular Density and Area of Radial Peripapillary Capillaries Changes in Myopic Individuals: A Wide-Field OCT Angiography Study.

Jingsai Gu, Yishuang Xu, Di Xiao, Yang Wang, Wenwen Lei, Zhen Chen, Dihao Hua

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Article in Translational vision science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jingsai GuDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China.
Yishuang XuDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China.
Di XiaoDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China.
Yang WangDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China.
Wenwen LeiThe First People's Hospital of Guangshui City, Guangshui, China.
Zhen ChenDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China.
Dihao HuaDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Using swept-source optical coherence tomography (SS-OCT) to explore the effect of high myopia on superficial retina vascular density (SVD) of the peripheral region and the area of radial peripapillary capillaries (RPCs). Methods: In this cross-sectional study, a total of 91 volunteers (34 male subjects and 57 female subjects) were recruited and 34 individuals in the high myopic group (group A) and 57 individuals in the low myopic group (group B). Using the wide-field OCT-angiography (OCTA; 24 × 20 mm, 120 degrees angular field) compared the peripheral SVD and the area of RPC between the two groups and investigated its correlation with ocular axial length and diopter. Results: Peripheral SVD of group B around the supratemporal (SVD1), supranasal (SVD2), infratemporal (SVD3), and infranasal (SVD4) directions were significantly higher than those of group A (all P < 0.05). The RPC area of group B around the supranasal (RPC2) and infranasal (RPC4) were significantly larger than that of group A (all P < 0.01). Ocular axial length and diopter were significantly correlated with SVD2 and SVD4 (all P < 0.05), and they also have a significant correlation with the supratemporal (RPC1), RPC2, and RPC4 (all P < 0.05). Conclusions: Peripheral SVD was decreased and the RPC area was mainly reduced on the nasal side in the high myopic group. Peripheral SVD and area of RPC are significantly correlated with ocular axial length and diopter. Translational Relevance: The wide-field OCTA can be used for new detection of myopia's impact on the retinal peripheral SVD and area of peripapillary RPC, offering new insights into the progression of myopia.

Indexed as

CapillariesRetinal VesselsTomography, Optical CoherenceAdultAxial Length, EyeCross-Sectional StudiesFemaleFluorescein AngiographyHumansMaleMicrovascular DensityMiddle AgedMyopiaOptic DiskYoung Adult

Identifiers

PMID39292467
PMCPMC11412621

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.