Evidence map›Paper›PMID 39292408›Full record

ArticleJournal of cardiovascular translational research2025

Assessment of CMR Feature-Tracking Age- and Sex-Dependent Right Ventricular Strain in a Healthy Caucasian Cohort.

Jan Eckstein, Hermann Körperich, Oliver M Weber, Wolfgang Burchert, Volodymyr Pugachov, Oleksandra Demydiuk, Misagh Piran

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jan EcksteinInstitut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum und Universität Bielefeld Medizinische Fakultät OWL, Bad Oeynhausen, Germany.
Hermann KörperichInstitut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum und Universität Bielefeld Medizinische Fakultät OWL, Bad Oeynhausen, Germany. hkoerperich@hdz-nrw.de.ORCID 0000-0002-5425-8440
Oliver M WeberPhilips Clinical Science, Hamburg, Germany.
Wolfgang BurchertInstitut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum und Universität Bielefeld Medizinische Fakultät OWL, Bad Oeynhausen, Germany.
Volodymyr PugachovInstitut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum und Universität Bielefeld Medizinische Fakultät OWL, Bad Oeynhausen, Germany.
Oleksandra DemydiukInstitut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum und Universität Bielefeld Medizinische Fakultät OWL, Bad Oeynhausen, Germany.
Misagh PiranInstitut für Radiologie, Nuklearmedizin und Molekulare Bildgebung, Herz- und Diabeteszentrum NRW, Universitätsklinikum der Ruhr-Universität Bochum und Universität Bielefeld Medizinische Fakultät OWL, Bad Oeynhausen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Right ventricular (RV) strain offers crucial diagnostic insights in cardiovascular and pulmonary disorders. Nonetheless, the absence of established reference values impedes its clinical implementation. Utilizing CMR-feature tracking, age- and gender-dependent RV strains were systematically assessed in 175 heart-healthy Caucasians, 97 females, median 32.5 years. RV global longitudinal strain (GLS) was greater in females than males (median -26.8% (-28.3;-24.1) vs. -24.4 ± 3.0%; p < 0.001), whereby radial and circumferential strain remained comparable. Age subgroups exhibited increased RV-GLS for group B (30-50 years) (-26.0 ± 3.1% vs. -24.4 ± 3.2%; p = 0.011) and group C (> 50 years) (-26.7 ± 2.3% vs. -24.4 ± 3.2%; p < 0.001) compared to group A (< 30 years). High intra-class correlation coefficients (ICC) were exhibited by intrarater variability (ICC = 0.86-0.95) and moderate levels for interrater variability (ICC = 0.50-0.73). CMR-feature tracking provides a fair quantification method of age- and gender-specific normal RV strain values, demonstrating that higher RV-GLS is linked to female gender and advancing age within a healthy Caucasian cohort.

Indexed as

Heart VentriclesMagnetic Resonance Imaging, CineMyocardial ContractionVentricular Function, RightWhite PeopleAdultAgedAge FactorsBiomechanical PhenomenaFemaleHealthy VolunteersHumansMaleMiddle AgedObserver VariationPredictive Value of TestsAge-dependencyCardiac magnetic resonance imagingFeature trackingGender-dependencyNormal valuesReproducibilityRight ventricular strain and strain rate

Identifiers

PMID39292408
PMCPMC11885332

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.