Evidence map›Paper›PMID 39291862›Full record

SynthesisCancer medicine2024

Barriers, facilitators, and other factors associated with health behaviors in childhood, adolescent, and young adult cancer survivors: A systematic review.

Ismay A E de Beijer, Eline Bouwman, Renée L Mulder, Philippa Steensma, Morven C Brown, Vera Araújo-Soares, Magdalena Balcerek, Edit Bardi, Jeanette Falck Winther, Line Elmerdahl Frederiksen and 22 more

Abstract readSystematic Review
In one paragraph

Synthesis in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Self-reported late effects and chronic fatigue, information needs and follow-up in long-term survivors of Hodgkin lymphoma-a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  7. Article
  8. Dietary intervention among young cancer survivors within the CARE for CAYA program.Journal of cancer survivorship : research and practice · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Ismay A E de BeijerPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID 0009-0000-5891-2959
Eline BouwmanDepartment of Hematology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.ORCID 0000-0002-9149-9745
Renée L MulderPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Philippa SteensmaPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Morven C BrownPopulation Health Sciences Institute, Centre for Cancer, Newcastle University, Newcastle upon Tyne, UK.
Vera Araújo-SoaresCenter for Preventive Medicine and Digital Health, Department for Prevention, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Magdalena BalcerekDepartment of Pediatric Oncology and Hematology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.
Edit BardiSt Anna Children's Hospital, Vienna, Austria.
Jeanette Falck WintherChildhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0002-3440-5108
Line Elmerdahl FrederiksenChildhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.
Marloes van GorpPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Sara ObertiDOPO clinic, Department of Hematology/Oncology, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Rebecca J van KalsbeekPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Tomas KepakInternational Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
Katerina KepakovaInternational Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
Hannah GsellChildhood Cancer International Europe, Vienna, Austria.
Anita KienesbergerChildhood Cancer International Europe, Vienna, Austria.
Raphaële van LitsenburgPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Luzius MaderChildhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.
Gisela MichelFaculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Monica MuracaDOPO clinic, Department of Hematology/Oncology, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Selina R van den OeverPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Helena J H van der PalPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Katharina RoserFaculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Roderick SkinnerGreat North Children's Hospital, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.ORCID 0000-0002-1162-675X
Iridi StolmanDepartment of Hematology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Anne UyttebroeckDepartment of Oncology, Paediatric Oncology, KU Leuven, Department of Paediatric Haematology and Oncology, University Hospitals Leuven, Leuven, Belgium.
Leontien C M KremerPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Jacqueline LoonenDepartment of Hematology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Elvira C van DalenPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Saskia M F PluijmPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
PanCareFollowUp Consortium

Funding

HORIZON EUROPE Framework Programme 824982
6 · The paper itself

Abstract

backgroundHealthy behaviors are paramount in preventing long-term adverse health outcomes in childhood, adolescent, and young adult (CAYA) cancer survivors. We systematically reviewed and synthesized existing literature on barriers, facilitators, and other factors associated with health behaviors in this population.

methodsMEDLINE and PsycInfo were searched for qualitative and quantitative studies including survivors aged 16-50 years at study, a cancer diagnosis ≤25 years and ≥2 years post diagnosis. Health behaviors included physical activity, smoking, diet, alcohol consumption, sun exposure, and a combination of these behaviors (defined as health behaviors in general).

resultsBarriers, facilitators, and other factors reported in ≥2 two studies were considered relevant. Out of 4529 studies, 27 were included (n = 31,905 participants). Physical activity was the most frequently examined behavior (n = 12 studies), followed by smoking (n = 7), diet (n = 7), alcohol (n = 4), sun exposure (n = 4), and health behavior in general (n = 4). Relevant barriers to physical activity were fatigue, lack of motivation, time constraints, and current smoking. Relevant facilitators were perceived health benefits and motivation. Influence of the social environment and poor mental health were associated with more smoking, while increased energy was associated with less smoking. No relevant barriers and facilitators were identified for diet, alcohol consumption, and sun exposure. Barriers to healthy behavior in general were unmet information needs and time constraints whereas lifestyle advice, information, and discussions with a healthcare professional facilitated healthy behavior in general. Concerning other factors, women were more likely to be physically inactive, but less likely to drink alcohol and more likely to comply with sun protection recommendations than men. Higher education was associated with more physical activity, and lower education with more smoking.

conclusionThis knowledge can be used as a starting point to develop health behavior interventions, inform lifestyle coaches, and increase awareness among healthcare providers regarding which survivors are most at risk of unhealthy behaviors.

Indexed as

Cancer SurvivorsExerciseHealth BehaviorAdolescentAdultAlcohol DrinkingChildDietFemaleHumansMaleMiddle AgedNeoplasmsSmokingYoung AdultbarriersCAYA cancer survivorsfacilitatorsfactorshealth behaviorshealthy lifestylepediatric oncologysystematic review

Identifiers

PMID39291862
PMCPMC11192647

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.