Trial reportBJOG : an international journal of obstetrics and gynaecology2025
Differences in Factors Associated With Preterm and Term Stillbirth: A Secondary Cohort Analysis of the DESiGN Trial.
Trial report in BJOG : an international journal of obstetrics and gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions to Address Disparities in Perinatal Outcomes by Ethnicity: A Systematic Review.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Cervical ripening with mechanical method vs oral misoprostol in pregnancies with elevated BMI: a cohort study.Archives of gynecology and obstetrics · 2026Article
- Gestational diabetes and stillbirth: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Stillbirth burden and associated factors in Chengdu, Western China: a population-based retrospective study, 2019-2024.BMC pregnancy and childbirth · 2025Article
- Factors associated with stillbirth in São Paulo, Brazil: FetRiskS - a multidisciplinary case-control study.BMC pregnancy and childbirth · 2025Article
- Ethnic Disparities in Perinatal Mortality and Associated Factors: A Nationwide Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Pregnancy and postpartum-related admissions to the intensive care unit at a tertiary centre in Northwest China: a 14-year retrospective study.BMC pregnancy and childbirth · 2025Article
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
objectiveTo identify whether maternal and pregnancy characteristics associated with stillbirth differ between preterm and term stillbirth.
designSecondary cohort analysis of the DESiGN RCT.
settingThirteen UK maternity units. POPULATION: Singleton pregnant women and their babies.
methodsMultiple logistic regression was used to assess whether the 12 factors explored were associated with stillbirth. Interaction tests assessed for a difference in these associations between the preterm and term periods.
main outcome measureStillbirth stratified by preterm (<37
resultsA total of 195 344 pregnancies were included. Six hundred and sixty-seven were stillborn (3.4 per 1000 births), of which 431 (65%) were preterm. Significant interactions were observed for maternal age, ethnicity, IMD, BMI, parity, smoking, PAPP-A, gestational hypertension, pre-eclampsia and gestational diabetes but not for chronic hypertension and pre-existing diabetes. Stronger associations with term stillbirth were observed in women with obesity compared to BMI 18.5-24.9 kg/m
conclusionDifferences in association exist between mothers experiencing preterm and term stillbirth. These differences could contribute to design of timely surveillance and interventions to further mitigate the risk of stillbirth.
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