Evidence map›Paper›PMID 39291196›Full record

ArticleKidney international reports2024

Immunoadsorption and Plasma Exchange are Comparable in Anti-Neutrophil Cytoplasmic Antibodies or Anti-Glomerular Basement Membrane Removal Kinetics.

Marion Sallee, Noémie Resseguier, Thomas Crepin, Daniel Bertin, Dominique Bertrand, Mickaël Bobot, Thierry Krummel, Nicolas Maillard, Julie Moussi-Frances, Marion Pelletier and 7 more

Abstract read
In one paragraph

Article in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. [Management of emergencies in rheumatology].Zeitschrift fur Rheumatologie · 2026
    Review
  2. Article
  3. [Management of emergencies in rheumatology].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
    Review
  4. Anti-glomerular basement membrane disease-treatment standard.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Marion SalleeAP-HM, Hôpital de la Conception, Centre de Néphrologie et Transplantation Rénale, Marseille, France.
Noémie ResseguierAix-Marseille Univ, CEReSS/UR 3279 - Health Services and Quality of Life Research, Marseille, France.
Thomas CrepinCHU de Besançon, Service de Néphrologie, Besançon, France.
Daniel BertinAP-HM, Hôpital de la Timone, Laboratoire d'Immunologie, Marseille, France.
Dominique BertrandCHU de Rouen, Service de Néphrologie, Rouen, France.
Mickaël BobotAP-HM, Hôpital de la Conception, Centre de Néphrologie et Transplantation Rénale, Marseille, France.
Thierry KrummelCHU de Strasbourg, Service de Néphrologie, Strasbourg, France.
Nicolas MaillardCHU de Saint-Etienne, Service de Néphrologie, Saint-Etienne, France.
Julie Moussi-FrancesHôpital Saint-Joseph, Service de Néphrologie, Marseille, France.
Marion PelletierAP-HM, Hôpital de la Conception, Centre de Néphrologie et Transplantation Rénale, Marseille, France.
Pascale PoullinAP-HM, Hôpital de la Conception, Service d'Aphérèses, Marseille, France.
Cédric RafatAP-HP, Hôpital Tenon, Service de Néphrologie, Paris, France.
Thomas RobertAP-HM, Hôpital de la Conception, Centre de Néphrologie et Transplantation Rénale, Marseille, France.
Benjamin TerrierAP-HP, Hôpital Cochin, Service de Médecine interne, Paris, France.
Lionel RostaingCHU de Grenoble, Service de Néphrologie, Grenoble, France.
Stanislas FaguerCHU de Toulouse, Service de Néphrologie, Toulouse, France.
Noémie Jourde-ChicheAP-HM, Hôpital de la Conception, Centre de Néphrologie et Transplantation Rénale, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Apheresis allows the fast removal of autoantibodies in anti-glomerular basement membrane (anti-GBM) disease, and in severe antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis. The CINEVAS study tested whether immunoadsorption (IA) allowed a faster removal of ANCA and/or anti-GBM antibodies than plasma exchanges (PEx). Methods: CINEVAS was a prospective multicenter study comparing IA to PEx in consecutive patients with ANCA and/or anti-GBM vasculitides. The primary objective was the reduction rate in autoantibody titers between the beginning of the first and the end of the seventh apheresis session. Secondary objectives were number of sessions needed to obtain desired reduction rates; reduction rates of total Ig levels; tolerance of sessions; and patients' outcome. Results: The results of 38 patients (16 treated with IA and 22 with PEx), and 43 autoantibodies, were analyzed. There was no difference in the reduction rates in autoantibody titers between IA and PEx over 7 sessions (respectively 98% vs. 96%, Conclusions: IA and PEx were comparable in ANCA or anti-GBM removal kinetics, despite a faster reduction in total IgG with IA.

Indexed as

ANCA-associated vasculitisantibody removalanti-GBM diseaseimmunoadsorptionplasma exchanges

Identifiers

PMID39291196
PMCPMC11403088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.