Evidence map›Paper›PMID 39291168›Full record

ArticleBrain communications2024

Cognitive outcomes following unilateral magnetic resonance-guided focused ultrasound thalamotomy for essential tremor: findings from two cohorts.

Julie Petersen, Josh McGough, Georgia Gopinath, Nadia Scantlebury, Richa Tripathi, Cheryl Brandmeir, Silina Z Boshmaf, Nicholas J Brandmeir, Isabella J Sewell, Peter E Konrad and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Julie PetersenRockefeller Neuroscience Institute, West Virginia University School of Medicine, Morgantown, WV 26505, USA.
Josh McGoughRockefeller Neuroscience Institute, West Virginia University School of Medicine, Morgantown, WV 26505, USA.
Georgia GopinathHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Nadia ScantleburyHarquail Centre for Neuromodulation, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Richa TripathiJean and Paul Amos PD and Movement Disorders Program, Department of Neurology, Emory University School of Medicine, Atlanta, GA 30307, USA.
Cheryl BrandmeirRockefeller Neuroscience Institute, West Virginia University School of Medicine, Morgantown, WV 26505, USA.
Silina Z BoshmafHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Nicholas J BrandmeirDepartment of Neuroscience, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Isabella J SewellHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Peter E KonradDepartment of Neuroscience, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Agessandro AbrahaoHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.ORCID https://orcid.org/0000-0003-1142-2842
Ann MurrayDepartment of Neurology, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Benjamin LamHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Manish RanjanDepartment of Neurosurgery, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Clement HamaniHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Jessica FreyDepartment of Neurology, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Camryn RohringerHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Melissa McSweeneyHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
James J MahoneyRockefeller Neuroscience Institute, West Virginia University School of Medicine, Morgantown, WV 26505, USA.
Michael L SchwartzHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
Ali RezaiDepartment of Neuroscience, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Nir LipsmanHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.
David M ScarisbrickDepartment of Neuroscience, West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV 26505, USA.
Jennifer S RabinHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada  M4N 3M5.ORCID https://orcid.org/0000-0003-4754-2221

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

Magnetic resonance-guided, focused ultrasound thalamotomy is a neurosurgical treatment for refractory essential tremor. This study examined cognitive outcomes following unilateral magnetic resonance-guided, focused ultrasound thalamotomy, targeting the ventral intermediate nucleus of the thalamus for essential tremor. The research was conducted at two sites: Sunnybrook Research Institute in Toronto, Canada, and West Virginia University School of Medicine Rockefeller Neuroscience Institute in West Virginia, USA. The study focused on cognitive changes at both the group and individual levels. Patients with refractory essential tremor completed cognitive testing before and after magnetic resonance-guided, focused ultrasound thalamotomy at both sites. The cognitive testing assessed domains of attention, processing speed, working memory, executive function, language and learning/memory. Postoperative changes in cognition were examined using paired

Indexed as

cognitionessential tremormagnetic resonance–guided focused ultrasoundneuropsychologythalamotomy

Identifiers

PMID39291168
PMCPMC11406546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.