Evidence map›Paper›PMID 39291036›Full record

ArticleACS medicinal chemistry letters2024

Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases.

Michele Rossi, Bianca Martinengo, Eleonora Diamanti, Alessandra Salerno, Nicola Rizzardi, Romana Fato, Christian Bergamini, Andressa Souza de Oliveira, Thais de Araújo Marques Ferreira, Cleonice Andrade Holanda and 15 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Michele RossiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.
Bianca MartinengoDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.ORCID https://orcid.org/0000-0002-4239-8120
Eleonora DiamantiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.
Alessandra SalernoDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.
Nicola RizzardiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.
Romana FatoDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.
Christian BergaminiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.
Andressa Souza de OliveiraLaboratório de Desenvolvimento de Inovações Terapêuticas, Núcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasília 70910-900, Brazil.
Thais de Araújo Marques FerreiraLaboratório de Desenvolvimento de Inovações Terapêuticas, Núcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasília 70910-900, Brazil.
Cleonice Andrade HolandaLaboratório de Desenvolvimento de Inovações Terapêuticas, Núcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasília 70910-900, Brazil.
Luiz Antonio Soares RomeiroLaboratório de Desenvolvimento de Inovações Terapêuticas, Núcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID https://orcid.org/0000-0001-5679-0820
Maria de Nazaré Correia SoeiroLaboratório de Biologia Celular do Instituto Oswaldo Cruz, Fiocruz. Avenida Brasil 4365, Manguinhos, Rio de Janeiro CEP 21040360, Brazil.
Krislayne NunesLaboratório de Biologia Celular do Instituto Oswaldo Cruz, Fiocruz. Avenida Brasil 4365, Manguinhos, Rio de Janeiro CEP 21040360, Brazil.
Ludmila Ferreira de Almeida FiuzaLaboratório de Biologia Celular do Instituto Oswaldo Cruz, Fiocruz. Avenida Brasil 4365, Manguinhos, Rio de Janeiro CEP 21040360, Brazil.
Marcos Meuser BatistaLaboratório de Biologia Celular do Instituto Oswaldo Cruz, Fiocruz. Avenida Brasil 4365, Manguinhos, Rio de Janeiro CEP 21040360, Brazil.
Carlos A M FragaLaboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.ORCID https://orcid.org/0000-0001-6733-7079
Hamed E A AlkhalafSchool of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G43 2DX, United Kingdom.
Ehab Kotb ElmahallawyDepartamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), Facultad de Veterinaria, Universidad de Córdoba, Córdoba 14014, Spain.
Godwin U EbilomaSchool of Science, Engineering & Environment, University of Salford, Manchester M5 4NT, United Kingdom.
Harry P De KoningSchool of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G43 2DX, United Kingdom.ORCID https://orcid.org/0000-0002-9963-1827
Serena VittorioDepartment of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, Milan 20133, Italy.
Giulio VistoliDepartment of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, Milan 20133, Italy.ORCID https://orcid.org/0000-0002-3939-5172
Christophe BlanquartNantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, Nantes CRCI2NA, France.
Philippe BertrandUniversity of Poitiers IC2MP UMR CNRS 7285, 4, rue Michel Brunet - TSA 51106. B27, Poitiers cedex 9 86073, France.ORCID https://orcid.org/0000-0001-8171-2031
Maria Laura BolognesiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum - University of Bologna, Via Belmeloro 6, Bologna 40126, Italy.ORCID https://orcid.org/0000-0002-1289-5361

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The search for new drugs fulfilling One Health and Green Chemistry requirements is an urgent call. Here, for the first time, we envisaged developing SAHA analogues by starting from the cashew nutshell liquid (CNSL) agro-industrial waste and employing a metathesis approach. This sustainable combination (comprising principles #7 and #9) allowed a straightforward synthesis of compounds

Identifiers

PMID39291036
PMCPMC11403742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.