Evidence map›Paper›PMID 39291018›Full record

ArticleACS medicinal chemistry letters2024

SAR Study of 4,8-Disubstituted Pyrimido[5,4-

André Lopes, Sofia Teixeira, Nuno Santarém, Alessandro Greco, Angela Pagliaro, Oliver Keminer, Sheraz Gul, Anabela Cordeiro-da-Silva, Maria Alice Carvalho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

André LopesCentre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Braga, Portugal and Departamento de Química, Escola de Ciências da Universidade do Minho, Braga 4710-057, Portugal.ORCID https://orcid.org/0000-0001-6821-8936
Sofia TeixeiraCentre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Braga, Portugal and Departamento de Química, Escola de Ciências da Universidade do Minho, Braga 4710-057, Portugal.ORCID https://orcid.org/0000-0002-4086-0975
Nuno SantarémInstituto de Investigação e Inovação em Saúde, Universidade do Porto and Institute for Molecular and Cell Biology, University of Porto, Porto 4150-180, Portugal.
Alessandro GrecoDepartment of Pharmacy, University of Pisa, Via Bonanno 6, Pisa 56126, Italy.
Angela PagliaroDepartment of Pharmacy, University of Pisa, Via Bonanno 6, Pisa 56126, Italy.
Oliver KeminerFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg 22525, Germany.
Sheraz GulFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg 22525, Germany.ORCID https://orcid.org/0000-0003-2543-1643
Anabela Cordeiro-da-SilvaInstituto de Investigação e Inovação em Saúde, Universidade do Porto and Institute for Molecular and Cell Biology, University of Porto, Porto 4150-180, Portugal.ORCID https://orcid.org/0000-0003-2392-6087
Maria Alice CarvalhoCentre of Chemistry of University of Minho (CQUM), Campus de Gualtar, Braga, Portugal and Departamento de Química, Escola de Ciências da Universidade do Minho, Braga 4710-057, Portugal.ORCID https://orcid.org/0000-0002-8666-0362

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A set of new derivatives of 4,8-disubstituted pyrimido[5,4-

Identifiers

PMID39291018
PMCPMC11403736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.