ArticleCureus2024
Behind the Counter Danger: Pseudoephedrine-Induced Seizure in an Elderly Patient.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pseudoephedrine intoxication: sex-specific differences in clinical symptoms.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this case report, the potential of pseudoephedrine to induce seizures as a side effect in elderly patients is discussed. Pseudoephedrine is commonly used to relieve nasal congestion caused by allergies, colds, or sinusitis. Still, it has been linked to several side effects, such as cardiovascular events, nervous system toxicity, and drug interactions. The report presents the case of an 83-year-old man with a medical history of diabetes, hypertension, and dyslipidemia who experienced a generalized tonic-clonic seizure after taking an over-the-counter medication containing loratadine and pseudoephedrine. The discussion underscores the need for caution when prescribing pseudoephedrine to elderly patients, particularly those with a history of seizures or other neurological conditions, and recommends alternative treatments like nasal saline irrigation or other decongestants. The case highlights the importance of comprehensive neurological assessment and diagnostic testing in patients with seizures to identify the underlying cause and guide appropriate management. Additional research is necessary to better understand the potential risks and benefits of using pseudoephedrine in elderly patients and explore alternative options for treating nasal congestion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.