Moderate Aortic Stenosis-Advanced Imaging, Risk Assessment, and Treatment Strategies.

Rik Adrichem, Mark M P van den Dorpel, Alexander Hirsch, Marcel L Geleijnse, Ricardo P J Budde, Nicolas M Van Mieghem

Abstract readReview

In one paragraph

Review in Structural heart : the journal of the Heart Team, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Association Between AI-derived Thoracic Calcium Volume and Aortic Valve Calcification Quantified by Agatston Scoring.In vivo (Athens, Greece)
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rik AdrichemDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

Mark M P van den DorpelDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

Alexander HirschDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

Marcel L GeleijnseDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

Ricardo P J BuddeDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

Nicolas M Van MieghemDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moderate aortic stenosis is increasingly recognized as a disease entity with poor prognosis. Diagnosis of moderate aortic stenosis may be complemented by laboratory tests and advanced imaging techniques focused at detecting signs of cardiac damage such as increase of cardiac enzymes (N-terminal pro-B-type Natriuretic Peptide, troponin), left ventricular remodeling (hypertrophy, reduced left ventricular ejection fraction), or myocardial fibrosis. Therapy should include guideline-directed optimal medical therapy for heart failure. Patients with signs of cardiac damage may benefit from early intervention, which is the focus of several ongoing randomized controlled trials. As yet, no evidence-based therapy exists to halt the progression of aortic valve calcification.

Indexed as

Advanced imaging techniquesAortic valve interventionsCardiac damageModerate aortic stenosisRisk assessment

Identifiers

PMID39290682

DOI10.1016/j.shj.2023.100279

PMCPMC11403096

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.