Evidence map›Paper›PMID 39290676›Full record

ArticleStructural heart : the journal of the Heart Team2024

Quantitative Aortography Analysis of JenaValve's Trilogy Transcatheter Aortic Valve Implantation System in Patients With Aortic Regurgitation or Stenosis.

Tsung-Ying Tsai, Hesham Elzomor, Hendrik Wienemann, Pruthvi Chenniganahosahalli Revaiah, Ralph Stephan von Bardeleben, Alexander Tamm, Scot Garg, Osama Soliman, Yoshinobu Onuma, Hans R Figulla and 3 more

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In one paragraph

Article in Structural heart : the journal of the Heart Team, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tsung-Ying TsaiCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Hesham ElzomorCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Hendrik WienemannDepartment of Internal Medicine III - Cardiology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Pruthvi Chenniganahosahalli RevaiahCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Ralph Stephan von BardelebenHeart Valve Center, Heart and Vascular Center, Universitätsmedizin Mainz, Mainz, Germany.
Alexander TammHeart Valve Center, Heart and Vascular Center, Universitätsmedizin Mainz, Mainz, Germany.
Scot GargDepartment of Cardiology, Royal Blackburn Hospital, Blackburn, UK.
Osama SolimanCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Yoshinobu OnumaCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.
Hans R FigullaUniversity Heart Center Jena, Friedrich-Schiller University, Jena, Germany.
Matti AdamDepartment of Internal Medicine III - Cardiology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Tanja RudolphClinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Patrick W SerruysCORRIB Research Centre for Advanced Imaging and Core Laboratory, University of Galway, Galway, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: JenaValve's Trilogy transcatheter heart valve (THV) (JenaValve Inc, Irvine, CA) is the only Methods: Using the CAAS-A-Valve 2.1.2 software (Pie Medical Imaging, Maastricht, the Netherlands), an independent core lab retrospectively analyzed the aortograms of 88 consecutive patients (68 severe AR; 20 severe AS) receiving the JenaValve THV in three European centers. Video-densitometric AR was categorized by the regurgitant fraction (RF) as none/trace AR (RF ≤ 6%), mild (6% < RF ≤ 17%), and moderate/severe AR (RF > 17%). Results: Pre- and post-THV aortograms were analyzable in 17 (22.4%) and 47 (54.0%) patients, respectively. The main reasons preventing analysis were the descending aorta overlap of the outflow tract (30%) and insufficient frame count (6%). The median RF pre- and post-THV implant was 31.0% (interquartile range 21.5-38.6%) and 5.0% (interquartile range 1.0-7.0%, Conclusions: Quantitative aortography confirms the low rates of AR and the large reduction in RF following the implantation of Jenavalve's Trilogy THV, irrespective of implant indication. However, these limited data need corroborating in prospective studies using standardized acquisition protocols.

Indexed as

JenavalveParavalvular leakPure aortic regurgitationTranscatheter aortic valve implantationVideo-densitometry

Identifiers

PMID39290676
PMCPMC11403081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.