Evidence map›Paper›PMID 39290619›Full record

ReviewFrontiers in physiology2024

A new perspective on the regulation of glucose and cholesterol transport by mitochondria-lysosome contact sites.

Xiaolong Chen, Chun Guang Li, Xian Zhou, Minghua Zhu, Jing Jin, Ping Wang

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Transposing intensive care innovation from modern warfare to other resource-limited settings.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolong ChenSchool of Physical Education, Hangzhou Normal University, Hangzhou, China.
Chun Guang LiNICM Health Research Institute, Western Sydney University, Westmead, NSW, Australia.
Xian ZhouNICM Health Research Institute, Western Sydney University, Westmead, NSW, Australia.
Minghua ZhuDepartment of Cardiothoracic Surgery, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Jing JinSchool of Physical Education, Hangzhou Normal University, Hangzhou, China.
Ping WangSchool of Physical Education, Hangzhou Normal University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria and lysosomes play a very important role in maintaining cellular homeostasis, and the dysfunction of these organelles is closely related to many diseases. Recent studies have revealed direct interactions between mitochondria and lysosomes, forming mitochondria-lysosome contact sites that regulate organelle network dynamics and mediate the transport of metabolites between them. Impaired function of these contact sites is not only linked to physiological processes such as glucose and cholesterol transport but also closely related to the pathological processes of metabolic diseases. Here, we highlight the recent progress in understanding the mitochondria-lysosome contact sites, elucidate their role in regulating metabolic homeostasis, and explore the potential implications of this pathway in metabolic disorders.

Indexed as

cholesterol transportglucose transportinsulin resistancemitochondria-lysosome contact sitesnonalcoholic fatty liver disease

Identifiers

PMID39290619
PMCPMC11405319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.