Evidence map›Paper›PMID 39290539›Full record

ArticleJournal of advanced pharmaceutical technology & research

Evaluation of the methanol extract of BaiYangJie: Toxicology and protective effect against acute kidney injury.

Jiaxin Li, Lingjuan Zhou, Jinhui Wang, Lixia Zhang, Bin Xia, Guang Li, Jiahui Ren, Jiacheng Li

Abstract read
In one paragraph

Article in Journal of advanced pharmaceutical technology & research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Molecules (Basel, Switzerland) · 2026
    Article
  3. Journal of inflammation research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiaxin LiCollege of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, China.
Lingjuan ZhouThe ICU of People's Hospital of Xishuangbanna Dai Autonomous Prefecture, Jinghong, China.
Jinhui WangYunnan Branch, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Branch, China.
Lixia ZhangYunnan Branch, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Branch, China.
Bin XiaCollege of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, China.
Guang LiYunnan Branch, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Branch, China.
Jiahui RenYunnan Branch, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Branch, China.
Jiacheng LiCollege of Integrated Traditional Chinese and Western Clinical, Beijing University of Chinese Medicine DongFang College, Cangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BaiYangJie (BYJ) is a terrestrial perennial plant commonly used as a Dai medicine and has therapeutic effects on liver and kidney diseases. Cisplatin (CP), a chemotherapy drug, has good therapeutic effects but causes many side effects, including nephrotoxicity. This article investigated the toxicology of the methanol extract of BYJ (ME-BYJ) and its protective effect on CP-induced acute kidney injury (AKI) through pharmacological experiments. The results showed that the treated mice had no toxicological symptoms and no anatomical, physiological, or histological abnormalities. The BYJ-high-dose group showed significantly attenuated CP-induced AKI. It is concluded that ME-BYJ has the most significant protective effect on AKI at a dose of 8 g/kg and BYJ was not toxic.

Indexed as

Acute kidney injuryBaiYangJiecisplatintoxicology

Identifiers

PMID39290539
PMCPMC11404437

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.