Evidence map›Paper›PMID 39290498›Full record

ArticleOpen life sciences2024

TAK-242 alleviates diabetic cardiomyopathy via inhibiting pyroptosis and TLR4/CaMKII/NLRP3 pathway.

Xiaolong Zhao, Jing Zhang, Feng Xu, Longqi Shang, Qingquan Liu, Chunjian Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open life sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolong ZhaoSchool of Graduates, Dalian Medical University, Dalian, China.
Jing ZhangMedical Department, The Second Hospital of Dalian Medical University, Dalian City, China.
Feng XuSchool of Graduates, Dalian Medical University, Dalian, China.
Longqi ShangDepartment of Nursing, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, China.
Qingquan LiuDepartment of Cardiothoracic Surgery, The Fourth People's Hospital of Shenyang, No. 20 Huanghe South Street, Shenyang, 110000, Liaoning, China.
Chunjian ShenDepartment of Cardiothoracic Surgery, The Fourth People's Hospital of Shenyang, No. 20 Huanghe South Street, Shenyang, 110000, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic cardiomyopathy (DCM) is identified as a progressive disease that may lead to irreparable heart failure. Toll-like receptor (TLR) signaling is believed to be implicated in the pathogenesis of DCM. This study intended to explore the potential impact of Toll-like receptor 4 (TLR4) on DCM

Indexed as

CaMKII/NLRP3 pathwaydiabetic cardiomyopathyinflammasomepyroptosisTAK-242TLR4

Identifiers

PMID39290498
PMCPMC11406225

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.