Evidence map›Paper›PMID 39290290›Full record

ArticleHeliyon2024

Network pharmacology, molecular docking and experimental approaches of the anti-proliferative effects of

Sally Wambui Kamau, Mathew Piero Ngugi, Peter Githaiga Mwitari, Sospeter Ngoci Njeru

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sally Wambui KamauCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Kenya.
Mathew Piero NgugiDepartment of Biochemistry, Microbiology and Biotechnology, Kenyatta University, Kenya.
Peter Githaiga MwitariCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Kenya.
Sospeter Ngoci NjeruCenter for Traditional Medicine and Drug Research, Kenya Medical Research Institute, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical cancer, one of the lethal cancers among women, is a challenging disease to treat. The current therapies often come with severe side effects and the risk of resistance development. Traditional herbal medicine, with its potential to offer effective and less toxic options, is a promising avenue. This study was undertaken to investigate the potential of Methods: Results: The ethyl acetate extract of Conclusion: This study, for the first time, demonstrates the anti-proliferation effects of EARP and forms a firm foundation for further drug development studies.

Indexed as

Anti-proliferative activityCervical cancerCytotoxicityNetwork pharmacologyRhamnus prinoides

Identifiers

PMID39290290
PMCPMC11407055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.