Evidence map›Paper›PMID 39290201›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

Medial open wedge high tibial osteotomy is a viable option in young patients with advanced arthritis in a long-term follow-up.

Nifon K Gkekas, George A Komnos, Theodoros Mylonas, Georgios Chalatsis, Antonios A Koutalos, Michael E Hantes

Registry-linked trialAbstract read
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07493733 (Comparing Medial Proximal Tibial Angle Measurements on Full-leg Standing Radiographs and The Rosenberg View in Patients Undergoing High Tibial Osteotomy), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07493733 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparing Medial Proximal Tibial Angle Measurements on Full-leg Standing Radiographs and The Rosenberg View in Patients Undergoing High Tibial Osteotomy

TypeobservationalSponsorAssiut UniversityRan2026 to 2028Enrolled49ConditionsMedial Proximal Tibial AngleArmsX-ray
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Clinical Outcomes Following Medial Opening Wedge High Tibial Osteotomy in Patients With Medial Compartment Grade 4 Chondromalacia.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Medial open wedge high tibial osteotomy is a viable option in young patients with advanced arthritis in a long-term follow-up.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nifon K GkekasDepartment of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, Mezourlo, Greece.ORCID http://orcid.org/0000-0002-0368-0465
George A KomnosDepartment of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, Mezourlo, Greece.ORCID http://orcid.org/0000-0002-6832-0014
Theodoros MylonasDepartment of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, Mezourlo, Greece.ORCID http://orcid.org/0000-0002-1377-7826
Georgios ChalatsisDepartment of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, Mezourlo, Greece.ORCID http://orcid.org/0000-0001-6640-505X
Antonios A KoutalosDepartment of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, Mezourlo, Greece.ORCID http://orcid.org/0000-0003-1811-6290
Michael E HantesDepartment of Orthopaedic Surgery, School of Health Sciences, Faculty of Medicine, University of Thessaly, Mezourlo, Greece.ORCID http://orcid.org/0000-0001-9494-6048

Funding

None
6 · The paper itself

Abstract

purposeThis study aimed to evaluate the long-term outcomes of medial open wedge high tibial osteotomy (MOWHTO) as a treatment option for advanced medial compartment knee osteoarthritis (OA) Kellgren-Lawrence (K-L) III and IV.

methodsPatients with severe medial compartment arthritis, who underwent MOWHTO with locking plate between 2003 and 2015, were retrospectively reviewed. A locking plate for the osteotomy was utilized. Preoperative and postoperative patients' evaluation was performed using the International Knee Documentation Committee Score (IKDC), the Oxford Knee Score (OKS), the Knee Injury Osteoarthritis Outcome Score (KOOS) and the Short Form-12 Score (SF-12). Standardized standing whole-limb X-rays were taken to evaluate the mechanical tibiofemoral angle (mTFA) and proximal medial tibial angle (PMTA), and the severity of OA.

resultsA total of 32 patients, 35 knees (27 males, five females) of which 21 were classified as K-L Grade III and 14 as K-L Grade IV, and mean age 47.1 ± 9.17 years old, who were followed for 13.6 years (range 7-20 years), were included in the study. During the follow-up period, three knees required conversion to total knee replacement (91.5% survival rate). All clinical outcome scores (KOOS, OKS, IKDC and SF-12) showed a significant improvement compared to preoperative status (p < 0.05). Preoperative mTFA and PMTA were significantly corrected immediately after surgery and retained this improvement at the last follow-up.

conclusionMOWHTO with a locking plate is an effective method to treat severe medial compartments. Clinical and radiological results are satisfactory and the survival rate is 91.5%, at a mean follow-up of 13.6 years after the procedure. LEVEL OF EVIDENCE: Level IV.

Indexed as

Osteoarthritis, KneeOsteotomyTibiaAdultBone PlatesFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomehigh tibial osteotomyKellgren & Lawrence III–IVknee alignmentknee osteoarthritislong termyoung patients

Identifiers

PMID39290201
PMCPMC11848967

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.