Evidence map›Paper›PMID 39289760›Full record

Trial reportEuropean journal of medical research2024

Intraoperative pneumatic tourniquet application reduces soft-tissue microcirculation, but without affecting wound healing in calcaneal fractures.

Philipp Lichte, Felix M Bläsius, Bergita Ganse, Boyko Gueorguiev, Torsten Pastor, Sven Nebelung, Filippo Migliorini, Kajetan Klos, Ali Modabber, Mario F Scaglioni and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01264146 (Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01264146 nacompletednot on this map

Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?

TypeinterventionalSponsorRWTH Aachen UniversityRan2011 to 2012Enrolled20ConditionsMicrocirculation, Wound HealingArmsHBOT, Placebo (Sham)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Philipp LichteDepartment of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany. plichte@ukaachen.de.
Felix M BläsiusDepartment of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Bergita GanseWerner Siemens Foundation Endowed Chair of Innovative Implant Development, Saarland University, Homburg, Germany.
Boyko GueorguievAO Research Institute Davos, 7270, Davos, Switzerland.
Torsten PastorDepartment of Orthopaedic and Trauma Surgery, Cantonal Hospital Lucerne, 6000, Lucerne, Switzerland.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, 52074, Aachen, Germany.
Filippo MiglioriniDepartment of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Kajetan KlosGelenkzentrum Rhein-Main, Hochheim, Germany.
Ali ModabberDepartment of Oral and Maxillofacial Surgery, University Hospital of Aachen, Aachen, Germany.
Mario F ScaglioniDepartment of Hand- and Plastic Surgery, Lucerne Cantonal Hospital, Lucerne, Switzerland.
Clemens SchopperDepartment for Orthopedics and Traumatology, Kepler University Hospital GmbH, Johannes Kepler University Linz, Linz, Austria.
Frank HildebrandDepartment of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Matthias KnobeMedical Faculty, University of Zurich, 8091, Zurich, Switzerland. Matthias.knobe@uzh.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWound healing complications are a major challenge following the extended lateral approach in calcaneal fractures. Soft-tissue microcirculation plays an important role via the delivery of oxygen, nutrients, and the regulation of a local milieu. The aim of this clinical study was to examine the effect of intraoperative pneumatic tourniquet application on skin and subcutaneous microcirculation, and its impact on wound healing progression.

methodsPatients with calcaneal fractures were randomly assigned to two groups defined by a surgery conducted either with use or without use of a tourniquet. Blood flow (BF [AU]), tissue oxygen saturation (SO

resultsThirty-four patients (3 women and 31 men) with 37 calcaneal fractures were included. In 22 of them, the surgery was conducted with a tourniquet and in the other 15 without its use. A significant decrease of microcirculation, characterized by decreases in blood flow (p = 0.011) and tissue oxygenation (p = 0.023) was measured in 8 mm depth after inflating the tourniquet. However, these changes did not influence the time of postoperative wound healing.

conclusionThe use of a pneumatic tourniquet reduces deep microcirculation without affecting postoperative wound healing. Trial registration The study was registered in www. CLINICALTRIALS: gov (NCT01264146).

Indexed as

CalcaneusMicrocirculationTourniquetsWound HealingAdultAgedFemaleFractures, BoneHumansMaleMiddle AgedBlood supplyCapillariesFoot surgeryInjuryO2CSpectrophotometryTissue hypoxiaTrauma

Identifiers

PMID39289760
PMCPMC11406720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.