Evidence map›Paper›PMID 39289405›Full record

ArticleNature communications2024

Longitudinal deep neural networks for assessing metastatic brain cancer on a large open benchmark.

Katherine E Link, Zane Schnurman, Chris Liu, Young Joon Fred Kwon, Lavender Yao Jiang, Mustafa Nasir-Moin, Sean Neifert, Juan Diego Alzate, Kenneth Bernstein, Tanxia Qu and 6 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. An MRI Atlas of Regional Brain Vulnerability to Metastatic Disease.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Improved Survival and Prognostication in Melanoma Patients With Brain Metastases: An Update of the Melanoma Graded Prognostic Assessment.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Katherine E LinkDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-2387-0116
Zane Schnurman *Department of Neurosurgery, NYU Langone Health, New York, NY, USA.
Chris Liu *Department of Neurosurgery, NYU Langone Health, New York, NY, USA.
Young Joon Fred KwonDepartment of Radiology, NYU Langone Health, New York, NY, USA.
Lavender Yao JiangDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-2464-3281
Mustafa Nasir-MoinHarvard Medical School, Boston, MA, USA.ORCID 0000-0002-0389-1852
Sean NeifertDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.
Juan Diego AlzateDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.ORCID 0000-0001-5663-8722
Kenneth BernsteinDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.ORCID 0000-0001-9484-2601
Tanxia QuDepartment of Radiation Oncology, NYU Langone Health, New York, NY, USA.
Viola ChenEikon Therapeutics, New York, NY, USA.
Eunice YangColumbia University Vagelos College of Surgeons and Physicians, New York, NY, USA.
John G GolfinosDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.
Daniel OrringerDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.ORCID 0000-0001-6427-8376
Douglas KondziolkaDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA.
Eric Karl OermannDepartment of Neurosurgery, NYU Langone Health, New York, NY, USA. eric.oermann@nyulangone.org.ORCID 0000-0002-1876-5963

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
NCI NIH HHS P30 CA016087
6 · The paper itself

Abstract

The detection and tracking of metastatic cancer over the lifetime of a patient remains a major challenge in clinical trials and real-world care. Advances in deep learning combined with massive datasets may enable the development of tools that can address this challenge. We present NYUMets-Brain, the world's largest, longitudinal, real-world dataset of cancer consisting of the imaging, clinical follow-up, and medical management of 1,429 patients. Using this dataset we developed Segmentation-Through-Time, a deep neural network which explicitly utilizes the longitudinal structure of the data and obtained state-of-the-art results at small (<10 mm

Indexed as

BenchmarkingBrain NeoplasmsDeep LearningNeural Networks, ComputerAgedFemaleHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID39289405
PMCPMC11408643

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.