Evidence map›Paper›PMID 39289322›Full record

ArticleFEBS open bio2024

Solvation free energy in governing equations for DNA hybridization, protein-ligand binding, and protein folding.

Caroline Harmon, Austin Bui, Jasmin M Espejo, Marc Gancayco, Jennifer M Le, Juan Rangel, Daryl K Eggers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline HarmonChemistry Department, San José State University, San José, CA, USA.
Austin BuiChemistry Department, San José State University, San José, CA, USA.
Jasmin M EspejoChemistry Department, San José State University, San José, CA, USA.
Marc GancaycoChemistry Department, San José State University, San José, CA, USA.
Jennifer M LeChemistry Department, San José State University, San José, CA, USA.
Juan RangelChemistry Department, San José State University, San José, CA, USA.
Daryl K EggersChemistry Department, San José State University, San José, CA, USA.ORCID https://orcid.org/0000-0003-1915-5945

Funding

Role of Desolvation Energy in Model Biological ReactionsR15GM110654 · NIGMS · SAN JOSE STATE UNIVERSITY · PI EGGERS, DARYL K · 2015 to 2015
$289k
NIGMS NIH HHS R15 GM110654
6 · The paper itself

Abstract

This work examines the thermodynamics of model biomolecular interactions using a governing equation that accounts for the participation of bulk water in the equilibria. In the first example, the binding affinities of two DNA duplexes, one of nine and one of 10 base pairs in length, are measured and characterized by isothermal titration calorimetry (ITC) as a function of concentration. The results indicate that the change in solvation free energy that accompanies duplex formation (ΔG

Indexed as

DNAProtein BindingProtein FoldingThermodynamicsCalorimetryLactalbuminLigandsNucleic Acid HybridizationRibonuclease, PancreaticDNALactalbuminLigandsRibonuclease, Pancreaticbulk watercalorimetrydesolvationDNA duplexhydrationribonuclease inhibitor

Identifiers

PMID39289322
PMCPMC11532980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.