Evidence map›Paper›PMID 39289310›Full record

ReviewDiscover nano2024

Recent advances in two-dimensional materials for the diagnosis and treatment of neurodegenerative diseases.

Jin-Ha Choi, Izzati Haizan, Jeong-Woo Choi

Abstract readReview
In one paragraph

Review in Discover nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jin-Ha ChoiSchool of Chemical Engineering, Clean Energy Research Center, Jeonbuk National University, Jeonju, 54896, Republic of Korea.
Izzati HaizanSchool of Chemical Engineering, Clean Energy Research Center, Jeonbuk National University, Jeonju, 54896, Republic of Korea.
Jeong-Woo ChoiDepartment of Chemical and Biomolecular Engineering, Sogang University, Seoul, 04107, Republic of Korea. jwchoi@sogang.ac.kr.

Funding

National Research Foundation of Korea funded by the Ministry of Science and ICT RS-2023-00259341National Research Foundation of Korea (NRF) funded by the Ministry of Education 2016R1A6A1A03012845National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) 2022R1C1C1008797
6 · The paper itself

Abstract

With the size of the aging population increasing worldwide, the effective diagnosis and treatment of neurodegenerative diseases (NDDs) has become more important. Two-dimensional (2D) materials offer specific advantages for the diagnosis and treatment of NDDs due to their high sensitivity, selectivity, stability, and biocompatibility, as well as their excellent physical and chemical characteristics. As such, 2D materials offer a promising avenue for the development of highly sensitive, selective, and biocompatible theragnostics. This review provides an interdisciplinary overview of advanced 2D materials and their use in biosensors, drug delivery, and tissue engineering/regenerative medicine for the diagnosis and/or treatment of NDDs. The development of 2D material-based biosensors has enabled the early detection and monitoring of NDDs via the precise detection of biomarkers or biological changes, while 2D material-based drug delivery systems offer the targeted and controlled release of therapeutics to the brain, crossing the blood-brain barrier and enhancing treatment effectiveness. In addition, when used in tissue engineering and regenerative medicine, 2D materials facilitate cell growth, differentiation, and tissue regeneration to restore neuronal functions and repair damaged neural networks. Overall, 2D materials show great promise for use in the advanced treatment of NDDs, thus improving the quality of life for patients in an aging population.

Indexed as

Drug deliveryEarly diagnosisNeurodegenerative diseaseRegenerative medicineTwo-dimensional (2D) material

Identifiers

PMID39289310
PMCPMC11408446

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.