Evidence map›Paper›PMID 39289242›Full record

ArticleJapanese journal of radiology2025

MRI features of histological subtypes of thyroid cancer in comparison with CT findings: differentiation between anaplastic, poorly differentiated, and papillary thyroid carcinoma.

Takahide Maeda, Hiroki Kato, Tomohiro Ando, Masaya Kawaguchi, Hirofumi Shibata, Takenori Ogawa, Yoshifumi Noda, Fuminori Hyodo, Masayuki Matsuo

Abstract readComparative Study
In one paragraph

Article in Japanese journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Multimodal spectrum of approach in poorly differentiated thyroid carcinoma (an updated analysis).Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takahide MaedaDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Hiroki KatoDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan. kato.hiroki.w4@f.gifu-u.ac.jp.ORCID http://orcid.org/0000-0001-5926-1895
Tomohiro AndoDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Masaya KawaguchiDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Hirofumi ShibataDepartment of Otolaryngology, Gifu University, Gifu, Japan.
Takenori OgawaDepartment of Otolaryngology, Gifu University, Gifu, Japan.
Yoshifumi NodaDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Fuminori HyodoDepartment of Pharmacology, School of Medicine, Gifu University, Gifu, Japan.
Masayuki MatsuoDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the MRI features of the main histological subtypes of thyroid cancer and enable differentiation between anaplastic thyroid carcinoma (ATC), poorly differentiated thyroid carcinoma (PDTC), and papillary thyroid carcinoma (PTC). MATERIALS AND

methodsThis study included 79 patients with histopathologically proven thyroid cancer (14 ATCs, 8 PDTCs, and 57 PTCs) who underwent neck MRI. MRI images were retrospectively reviewed and compared between the three pathologies.

resultsThe maximum diameter was larger in ATCs and PDTCs than in PTCs (65.2 mm and 38.4 mm vs. 26.0 mm, p < 0.01). The signal intensity ratio of the solid components on T2-weighted images (T2WIs) was higher in ATCs than in PTCs (1.13 vs. 0.89, p < 0.05). The predominant signal intensity of the solid components on T2WI exhibited hyperintensity relative to the spinal cord in ATCs more frequently than in PTCs (71% vs. 30%, p < 0.01), whereas hypointensity was more frequent in PTCs than in ATCs and PDTCs (60% vs. 0% and 13%, p < 0.01). Intratumoral ring-shaped hypointensity on T2WI was more frequent in ATCs than in PDTCs and PTCs (64% vs. 13% and 18%, p < 0.01). An ill-defined margin was more frequent in ATCs and PDTCs than in PTCs (93% and 63% vs. 25%, p < 0.01). Extrathyroidal extension, tracheal invasion, esophageal invasion, vascular invasion, and venous thrombosis were more frequently observed in ATCs than in PTCs (p < 0.05).

conclusionsMRI could characterize the differences between ATCs, PDTCs, and PTCs.

Indexed as

CarcinomaMagnetic Resonance ImagingThyroid Carcinoma, AnaplasticThyroid NeoplasmsTomography, X-Ray ComputedAdultAgedAged, 80 and overCarcinoma, PapillaryDiagnosis, DifferentialFemaleHumansMaleMiddle AgedRetrospective StudiesThyroid Cancer, PapillaryAnaplastic thyroid carcinomaMRIPapillary thyroid carcinomaPoorly differentiated thyroid carcinomaThyroid cancer

Identifiers

PMID39289242
PMCPMC11790765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.