Evidence map›Paper›PMID 39289236›Full record

ArticleAAPS PharmSciTech2024

Development, Pharmacokinetics and Antimalarial Evaluation of Dose Flexible 3D Printlets of Dapsone for Pediatric Patients.

Adnan A Khan, Tahir Khuroo, Eman M Mohamed, Sathish Dharani, Kayalar Canberk, Xiaoyu Zhang, Lamba Omar Sangaré, Mathew A Kuttolamadom, Allison C Rice-Ficht, Ziyaur Rahman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AAPS PharmSciTech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adnan A KhanSchool of Engineering Medicine, Texas A&M University, Houston, Texas, 77030, USA.
Tahir KhurooTexas A&M Health Science Center, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Reynolds Medical Sciences Building, Suite 308, College Station, Texas, 77843, USA.
Eman M MohamedTexas A&M Health Science Center, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Reynolds Medical Sciences Building, Suite 308, College Station, Texas, 77843, USA.
Sathish DharaniTexas A&M Health Science Center, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Reynolds Medical Sciences Building, Suite 308, College Station, Texas, 77843, USA.
Kayalar CanberkTexas A&M Health Science Center, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Reynolds Medical Sciences Building, Suite 308, College Station, Texas, 77843, USA.
Xiaoyu ZhangDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.
Lamba Omar SangaréDepartment of Biology, Texas A&M University, College Station, Texas, 77843, USA.
Mathew A KuttolamadomDepartment of Engineering Technology & Industrial Distribution, College of Engineering, Texas A&M University, College Station, Texas, 77843, USA.
Allison C Rice-FichtDepartment of Cell Biology and Genetics, School of Medicine, Texas A&M Health Science Center, Texas A&M University, College Station, Texas, 77843, USA.
Ziyaur RahmanTexas A&M Health Science Center, Irma Lerma Rangel School of Pharmacy, Texas A&M University, Reynolds Medical Sciences Building, Suite 308, College Station, Texas, 77843, USA. rahman@tamu.edu.ORCID http://orcid.org/0000-0002-0402-825X

Funding

Dose Flexible Combination 3D-Printed Delivery Systems for Antiviral Therapy in ChildrenR01HD112077 · NICHD · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI MANSOOR A KHAN, Ziyaur Rahman · 2023 to 2026
$2.2M
Age-appropriate flexible pediatric drug delivery systemsR56HD106612 · NICHD · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI KHAN, MANSOOR A · 2021 to 2022
$677k
NICHD NIH HHS R01 HD112077NICHD NIH HHS R56 HD106612
6 · The paper itself

Abstract

The focus of current studies was to fabricate dose flexible printlets of dapsone (DDS) for pediatric patients by selective laser sintering (SLS) 3D printing method, and evaluate its physicochemical, patient in-use stability, and pharmacokinetic attributes. Eight formulations were fabricated using Kollicoat

Indexed as

AntimalarialsDapsonePrinting, Three-DimensionalRats, Sprague-DawleyAnimalsCalorimetry, Differential ScanningChemistry, PharmaceuticalChildDrug CompoundingDrug StabilityExcipientsHumansMaleRatsSolubilityTabletsAntimalarialsDapsoneExcipientsTabletsanti-parasitic efficacydapsonedissolutionpharmacokineticprintletsselective laser sintering

Identifiers

PMID39289236
PMCPMC12218905

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.