Evidence map›Paper›PMID 39288994›Full record

ArticleGenome research2024

Full-length RNA transcript sequencing traces brain isoform diversity in house mouse natural populations.

Wenyu Zhang, Anja Guenther, Yuanxiao Gao, Kristian Ullrich, Bruno Huettel, Aftab Ahmad, Lei Duan, Kaizong Wei, Diethard Tautz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenyu ZhangShaanxi Key Laboratory of Qinling Ecological Intelligent Monitoring and Protection, School of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710129, China; wyzhang@nwpu.edu.cn tautz@evolbio.mpg.de.ORCID 0000-0002-2507-3033
Anja GuentherDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Ploen 24306, Germany.
Yuanxiao GaoSchool of Mathematics and Data Science, Shaanxi University of Science and Technology, Xi'an 710021, China.ORCID 0000-0002-6719-8299
Kristian UllrichDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Ploen 24306, Germany.
Bruno HuettelMax-Planck-Genome-Centre Cologne, MPI for Plant Breeding Research, Cologne 50829, Germany.
Aftab AhmadShaanxi Key Laboratory of Qinling Ecological Intelligent Monitoring and Protection, School of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710129, China.
Lei DuanShaanxi Key Laboratory of Qinling Ecological Intelligent Monitoring and Protection, School of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710129, China.
Kaizong WeiShaanxi Key Laboratory of Qinling Ecological Intelligent Monitoring and Protection, School of Ecology and Environment, Northwestern Polytechnical University, Xi'an 710129, China.
Diethard TautzDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Ploen 24306, Germany; wyzhang@nwpu.edu.cn tautz@evolbio.mpg.de.ORCID 0000-0002-0460-5344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to generate multiple RNA transcript isoforms from the same gene is a general phenomenon in eukaryotes. However, the complexity and diversity of alternative isoforms in natural populations remain largely unexplored. Using a newly developed full-length transcript enrichment protocol with 5' CAP selection, we sequenced full-length RNA transcripts of 48 individuals from outbred populations and subspecies of

Indexed as

BrainPolymorphism, Single NucleotideRNA IsoformsAlternative SplicingAnimalsExonsGenetic VariationMicePhylogenyProtein IsoformsSequence Analysis, RNAProtein IsoformsRNA Isoforms

Identifiers

PMID39288994
PMCPMC11610456

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.