Trial reportAmerican journal of respiratory and critical care medicine2024
Lung-Protective Mechanical Ventilation in Patients with Severe Acute Brain Injury: A Multicenter Randomized Clinical Trial (PROLABI).
Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph
Trial report in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Respiratory mechanics modifies the impact of ventilator settings on clinical outcome in patients with acute brain injury.Intensive care medicine · 2026Article
- Mechanical Ventilation Practices in Traumatic Brain Injury: A Systematic Review of Contemporary Evidence.Cureus · 2026Review
- ARDS management in trauma patients.Intensive care medicine · 2026Review
- Balancing lung and brain: physiological strategies for ARDS management in acute brain injury.Intensive care medicine · 2026Review
- Sedation as an Immunomodulator of Inflammatory Responses in the Lung-Brain Axis of ARDS.International journal of molecular sciences · 2026Review
- Setting mechanical ventilation in patients with acute brain injury: ultra-low dynamic driving pressure for better outcomes?Intensive care medicine · 2026Article
- First Breath Matters: Out-of-Hospital Mechanical Ventilation in Patients with Traumatic Brain Injury.Journal of clinical medicine · 2025Review
- Bridging brain and lung: optimizing mechanical ventilation in acute brain injury.Journal of anesthesia, analgesia and critical care · 2025Review
- Observational
- Efficiency of a Protective Mode of Mechanical Ventilation in Patients with Severe Traumatic Brain Injury Complicated by Acute Respiratory Distress Syndrome.Brain sciences · 2025Article
- Brain Protective Ventilation Strategies in Severe Acute Brain Injury.Current neurology and neuroscience reports · 2025Review
- Management Patterns and Outcomes of Invasive Mechanical Ventilation in Patients With Cardiogenic Shock.JACC. Advances · 2025Article
- Traumatic brain injury management in the intensive care unit: standard of care and knowledge gaps.Intensive care medicine · 2025Review
- Correspondence about the VENTIBRAIN study.Intensive care medicine · 2025Article
- Review of Ventilation in Traumatic Brain Injury.Respiratory care · 2025Review
- Beyond the Lungs: Extrapulmonary Effects of Non-Invasive and Invasive Ventilation Strategies.Journal of clinical medicine · 2025Review
- Ventilation practices in acute brain injured patients and association with outcomes: the VENTIBRAIN multicenter observational study.Intensive care medicine · 2025Observational
- Organ crosstalk: brain-lung interaction.Frontiers in medicine · 2025Review
- Does Lung Protective Ventilation Work in Acute Brain Injury?American journal of respiratory and critical care medicine · 2024Article
- Effect of low tidal volume ventilation on cerebral hemodynamics in patients with severe traumatic brain injury.Journal of anaesthesiology, clinical pharmacologyArticle
Corrections and comments
- Commented on by
Authors and funding
25 authors.
Luciana MasciaDepartment of Experimental Medicine (DIMES), Campus Ecotekne, University of Salento, Lecce, Italy.
Vito FanelliDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Alice MistrettaDepartment of Anesthesia and Intensive Care Unit, Città della Salute e della Scienza di Torino University Hospital - Orthopedic and Trauma Center, Turin, Italy.
Matteo FilippiniDepartment of Anesthesiology, Intensive Care, and Emergency, Spedali Civili University Hospital, Brescia, Italy.
Mattia ZaninDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Maurizio BerardinoDepartment of Anesthesia and Intensive Care Unit, Città della Salute e della Scienza di Torino University Hospital - Orthopedic and Trauma Center, Turin, Italy.
Anna Teresa MazzeoDepartment of Adult and Pediatric Pathology, University of Messina, Messina, Italy.
Anselmo CaricatoNeurosurgical Intensive Care Unit and.
Massimo AntonelliDepartment of Anesthesiology and Intensive Care Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Francesco Della CorteDepartment of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.
Francesca GrossiAnesthesiology and Intensive Care Medicine, Maggiore della Carità University Hospital, Novara, Italy.
Marina MunariInstitute of Anesthesia and Intensive Care, University Hospital of Padua, Padua, Italy.
Massimiliano CaravelloInstitute of Anesthesia and Intensive Care, University Hospital of Padua, Padua, Italy.
Francesco AlessandriDepartment of General Surgery and Organ Transplantation Unit, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Irene CavalliDepartment of Medical and Surgical Sciences (DIMEC) and.
Mario MezzapesaDepartment of General Surgery and Organ Transplantation Unit, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Lucia SilvestriDepartment of General Surgery and Organ Transplantation Unit, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Marilena Casartelli LivieroDepartment of Anesthesia and Intensive Care, Integrated University Hospital of Verona, Verona, Italy.
Paolo ZanattaDepartment of Anesthesia and Intensive Care, Integrated University Hospital of Verona, Verona, Italy.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
Giuseppe CiterioSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Claudia FilippiniDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Paola RucciDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Frank A RasuloDepartment of Anesthesiology, Intensive Care, and Emergency, Spedali Civili University Hospital, Brescia, Italy.
Tommaso TonettiDepartment of Medical and Surgical Sciences (DIMEC) and.ORCID 0000-0001-9676-3595
Funding
Università degli Studi di Torino ex 60% 2012-2015
Abstract
PubMed holds no abstract for this paper.
Indexed as
Positive-Pressure RespirationRespiration, ArtificialRespiratory Distress SyndromeAdultAgedBrain InjuriesFemaleHumansMaleMiddle AgedTidal VolumeTreatment Outcomeacute brain injuryacute respiratory distress syndromelung-protective ventilation
Identifiers
PMID
39288368What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.