Evidence map›Paper›PMID 39288355›Full record

ArticleThe journal of physical chemistry letters2024

Harnessing Light for G-Quadruplex Modulation: Dual Isomeric Effects of an

Marta Dudek, Lucía López-Pacios, Nasim Sabouri, Juan J Nogueira, Lara Martinez-Fernandez, Marco Deiana

Abstract read
In one paragraph

Article in The journal of physical chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Light-Controlled Folding and Chiroptical Sensing of G-Quadruplex DNA.The journal of physical chemistry letters · 2026
    Article
  2. Article
  3. Light-Activated Molecules Targeting G-Quadruplex Nucleic Acids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marta DudekInstitute of Advanced Materials, Faculty of Chemistry, Wrocław University of Science and Technology, Wyb. Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0001-6749-0903
Lucía López-PaciosDepartamento de Química, Facultad de Ciencias, Universidad Autónoma de Madrid, Campus de Excelencia UAM-CSIC, Cantoblanco, 28049 Madrid, Spain.ORCID 0009-0007-6892-3652
Nasim SabouriDepartment of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.ORCID 0000-0002-4541-7702
Juan J NogueiraDepartamento de Química, Facultad de Ciencias, Universidad Autónoma de Madrid, Campus de Excelencia UAM-CSIC, Cantoblanco, 28049 Madrid, Spain.ORCID 0000-0001-7419-5670
Lara Martinez-FernandezDepartamento de Química Física de Materiales, Instituto de Química Física Blas Cabrera, CSIC, 28006 Madrid, Spain.ORCID 0000-0001-5361-9390
Marco DeianaInstitute of Advanced Materials, Faculty of Chemistry, Wrocław University of Science and Technology, Wyb. Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-7815-4494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

G-quadruplexes (G4s) are important therapeutic and photopharmacological targets in cancer research. Small-molecule ligands targeting G4s offer a promising strategy to block DNA transactions and induce genetic instability in cancer cells. While numerous G4-ligands have been reported, relatively few examples exist of compounds whose G4-interactive binding properties can be modulated using light. Herein, we report the photophysical characterization of a novel

Indexed as

G-QuadruplexesLightAntineoplastic AgentsAzo CompoundsCell Line, TumorDNAHumansIsomerismLigandsAntineoplastic AgentsazobenzeneAzo CompoundsDNALigands

Identifiers

PMID39288355
PMCPMC11440583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.