Evidence map›Paper›PMID 39288174›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Glial

Peter Rodriguez, Vrinda Kalia, Cristina Fenollar-Ferrer, Chelsea L Gibson, Zayna Gichi, Andre Rajoo, Carson D Matier, Aidan T Pezacki, Tong Xiao, Lucia Carvelli and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. GlialProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Optical Imaging Demonstrates Tissue-Specific Metabolic Perturbations in Mblac1 Knockout Mice.IEEE journal of translational engineering in health and medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Peter RodriguezDepartment of Biological Sciences, Charles E. Schmidt College of Science, Boca Raton, FL 33412.
Vrinda KaliaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032.ORCID 0000-0003-2244-6663
Cristina Fenollar-FerrerLaboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, Bethesda, MD 20892.ORCID 0000-0003-4953-8891
Chelsea L GibsonDepartment of Biological Sciences, Charles E. Schmidt College of Science, Boca Raton, FL 33412.
Zayna GichiDepartment of Biomedical Science, Charles E. Schmidt College of Medicine, Jupiter, FL 33458.
Andre RajooDepartment of Biology, Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, FL 33458.ORCID 0009-0007-8179-2466
Carson D MatierDepartment of Chemistry, University of California, Berkeley, CA 94720.ORCID 0000-0002-1618-7944
Aidan T PezackiDepartment of Chemistry, University of California, Berkeley, CA 94720.ORCID 0000-0002-7321-462X
Tong XiaoDepartment of Chemistry, University of California, Berkeley, CA 94720.
Lucia CarvelliStiles-Nicholson Brain Institute, Florida Atlantic University, Jupiter, FL 33458.ORCID 0000-0001-8754-3777
Christopher J ChangDepartment of Chemistry, University of California, Berkeley, CA 94720.ORCID 0000-0001-5732-9497
Gary W MillerDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032.ORCID 0000-0001-8984-1284
Andy V KhamouiStiles-Nicholson Brain Institute, Florida Atlantic University, Jupiter, FL 33458.
Jana BoernerStiles-Nicholson Brain Institute, Florida Atlantic University, Jupiter, FL 33458.ORCID 0000-0001-7451-2154
Randy D BlakelyStiles-Nicholson Brain Institute, Florida Atlantic University, Jupiter, FL 33458.

Funding

Molecular Imaging Probes To Study Redox BiologyR01GM079465 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Christopher J. Chang · 2006 to 2026
$7.8M
Vesicular Modulation of Dopamine Neuron ToxicityR01ES023839 · NIEHS · EMORY UNIVERSITY · PI MILLER, GARY W · 2015 to 2025
$5.0M
Florida Department of Health (DOH) 22A01HHS | NIH (NIH) 79465HHS | NIH (NIH) ES 023839NIEHS NIH HHS R01 ES023839NIGMS NIH HHS R01 GM079465
6 · The paper itself

Abstract

Cuprous copper [Cu(I)] is an essential cofactor for enzymes that support many fundamental cellular functions including mitochondrial respiration and suppression of oxidative stress. Neurons are particularly reliant on mitochondrial production of ATP, with many neurodegenerative diseases, including Parkinson's disease, associated with diminished mitochondrial function. The gene

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCopperHomeostasisMitochondriaNeurogliaOxidative StressAnimalsCell SurvivalDopaminergic NeuronsNeuronsCaenorhabditis elegans ProteinsCopperC. eleganscopperglianeurodegenerationswip-10

Identifiers

PMID39288174
PMCPMC11441482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.