Evidence map›Paper›PMID 39288080›Full record

ArticleACS applied materials & interfaces2024

Physicochemical Changes of Apoferritin Protein during Biodegradation of Magnetic Metal Oxide Nanoparticles.

Ehsan Rahimi, Amin Imani, Donghoon Kim, Mohammad Rahimi, Lorenzo Fedrizzi, Arjan Mol, Edouard Asselin, Salvador Pané, Maria Lekka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ehsan RahimiDepartment of Materials Science and Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands.ORCID 0000-0002-7128-8940
Amin ImaniDepartment of Materials Engineering, The University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.ORCID 0000-0003-1703-0604
Donghoon KimLaboratory for Multiscale Materials Experiments, Paul Scherrer Institute, Forschungstrasse 111, Villigen 5232, Switzerland.
Mohammad RahimiDepartment of Mechanical Engineering, McMaster University, Hamilton, Ontario L8S 3L8, Canada.
Lorenzo FedrizziPolytechnic Department of Engineering and Architecture, University of Udine, 33100 Udine, Italy.
Arjan MolDepartment of Materials Science and Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands.ORCID 0000-0003-1810-5145
Edouard AsselinDepartment of Materials Engineering, The University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.ORCID 0000-0001-9492-4949
Salvador PanéMulti-Scale Robotics Lab, Institute of Robotics and Intelligent Systems, Department of Mechanical and Process Engineering, ETH Zurich, Tannenstrasse 3, Zurich 8092, Switzerland.ORCID 0000-0003-0147-8287
Maria LekkaCIDETEC, Basque Research and Technology Alliance (BRTA), Donostia-San Sebastián 20014, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biodegradation of therapeutic magnetic-oxide nanoparticles (MONPs) in the human body raises concerns about their lifespan, functionality, and health risks. Interactions between apoferritin proteins and MONPs in the spleen, liver, and inflammatory macrophages significantly accelerate nanoparticle degradation, releasing metal ions taken up by apoferritin. This can alter the protein's biological structure and properties, potentially causing health hazards. This study examines changes in apoferritin's shape, electrical surface potential (ESP), and protein-core composition after incubation with cobalt-ferrite (CoFe

Indexed as

ApoferritinsCobaltFerric CompoundsHumansMagnetite NanoparticlesMicroscopy, Atomic ForceOxidesApoferritinsCobaltcobalt ferriteFerric CompoundsMagnetite NanoparticlesOxidesapoferritin proteinbiodegradationKelvin probe force microscopyoxide nanoparticlesprotein surface potential

Identifiers

PMID39288080
PMCPMC11450718

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.