Evidence map›Paper›PMID 39287838›Full record

ArticleMikrochimica acta2024

Carbon dots based AuAg@AuNPs with oxidase-like activity for SERS dual-readouts detection of D-penicillamine.

Zhao Zhao, Yang Jiao, Dezhi Yang, Yaling Yang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhao ZhaoFaculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Province, 650500, China.
Yang JiaoFaculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Province, 650500, China.
Dezhi YangFaculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Province, 650500, China.
Yaling YangFaculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Province, 650500, China. yilyil8@163.com.

Funding

Analysis and Testing Foundation of Kunming University of Science and Technology No.2023M20222218057
6 · The paper itself

Abstract

An oxidase (OXD) -like AuAg@AuNPs nanozyme was prepared by Au seeds growth using dopamine carbon dots as reducing and capping agents. The AuAg@AuNPs show excellent OXD-like and surface-enhanced Raman spectroscopy (SERS) activities and can oxidize the non-Raman-active leucomalachite green (LMG) into the Raman-active malachite green (MG). The research displays that D-penicillamine (D-PA) can effectively inhibit the OXD-like activity of Au@AgNPs and enhance the SERS signals as substrate. It is attributed to the formation of S-Au bond due to thiol (-SH) in D-PA. Therefore, a highly sensitive and specific SERS dual-readout sensing platform was proposed to assay D-PA with a limit of detection of 0.1 μg/mL (direct SERS mode) and 6.64 μg/L (indirect SERS mode). This approach was successfully used to determine D-PA in actual pharmaceutical formulations.

Indexed as

CarbonGoldLimit of DetectionMetal NanoparticlesPenicillamineSilverSpectrum Analysis, RamanOxidoreductasesQuantum DotsCarbonGoldOxidoreductasesPenicillamineSilverAuAg@AuNPs nanozymeDopamine carbon dotsD-penicillamineSERS dual-readout

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.