Evidence map›Paper›PMID 39287724›Full record

ArticleBulletin of experimental biology and medicine2024

Approbation of a Homologous Model of the Antitumor Vaccine Based on Mature Mouse Dendritic Cells to Study the Biodistribution of the Cell Product.

T L Nekhaeva, I D Laskov, E I Fedoros, A B Danilova, M N Yurova, M L Tyndyk, E D Ermakova, N V Emelyanova, N A Efremova, A V Grigorevskaya and 2 more

Abstract read
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Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

T L NekhaevaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia. nehaevat151274@mail.ru.
I D LaskovN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
E I FedorosN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
A B DanilovaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
M N YurovaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
M L TyndykN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
E D ErmakovaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
N V EmelyanovaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
N A EfremovaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
A V GrigorevskayaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
M A NekrasovaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
I A BalduevaN. N. Petrov National Medical Cancer Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homologous animal cell product was obtained in protocol developed for female BALB/c mice. Dendritic cell (DC) migration from the injection site into the draining lymph nodes was evaluated. The number of DC labeled with carboxyfluorescein succinimidyl ester (CFSE) in draining lymph nodes increased from 5.3% (16 h) to 13.3% (48 h) (p=0.028) with a maximum at 72 h (15.4%, p=0.003). The immunophenotype of CFSE-DC detected in murine lymph nodes corresponded to the immunophenotype of mature vaccine DCs: they expressed differentiation markers CD11c, CD80, CD83, and CD86 (p>0.05 vs initial DC).

Indexed as

Cancer VaccinesDendritic CellsLymph NodesMice, Inbred BALB CAnimalsAntigens, CDB7-1 AntigenB7-2 AntigenCD11c AntigenCD83 AntigenCell DifferentiationCell MovementFemaleFluoresceinsImmunoglobulinsImmunophenotyping5-(6)-carboxyfluorescein diacetate succinimidyl esterAntigens, CDB7-1 AntigenB7-2 AntigenCancer VaccinesCD11c AntigenCD83 AntigenFluoresceinsImmunoglobulinsMembrane GlycoproteinsSuccinimidesbiodistributiondendritic cellshomologous cell productpreclinical studies

Identifiers

PMID39287724

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.