Evidence map›Paper›PMID 39287685›Full record

ArticleThe Journal of cell biology2024

Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor.

Johannes Vincent Tromm, Dragomir Milovanovic

Abstract read
In one paragraph

Article in The Journal of cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biomolecular Condensates Can Induce Local Membrane Potentials.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Johannes Vincent TrommLaboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE) , Berlin, Germany.ORCID 0009-0006-9251-1335
Dragomir MilovanovicLaboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE) , Berlin, Germany.ORCID 0000-0002-6625-1879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two recent papers by Mehta et al. and Zhu et al. in this issue (https://doi.org/10.1083/jcb.202311191) discover that synaptotagmin-1, the primary calcium sensor at the synapse, forms biomolecular condensates, identifying a new layer of regulation in calcium-triggered synaptic vesicle exocytosis.

Indexed as

CalciumExocytosisSynapsesSynaptotagmin IAnimalsHumansSynaptic VesiclesCalciumSynaptotagmin I

Identifiers

PMID39287685
PMCPMC11408922

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.