Evidence map›Paper›PMID 39287543›Full record

ArticleRetina (Philadelphia, Pa.)2024

FACTORS ASSOCIATED WITH DELAYED DIAGNOSIS IN PATIENTS WITH PRIMARY VITREORETINAL LYMPHOMA.

Kenny Y Wang, Timothy T Xu, Rachel S Mogil, Allisa J Song, Launia J White, David O Hodge, Lauren A Dalvin

Abstract read
In one paragraph

Article in Retina (Philadelphia, Pa.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Ocular Imaging in Intraocular Lymphoma: A Review.Clinical & experimental ophthalmology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenny Y WangAlix School of Medicine, Mayo Clinic, Rochester, Minnesota.
Timothy T XuDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota; and.
Rachel S MogilDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota; and.
Allisa J SongDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota; and.
Launia J WhiteDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, Florida.
David O HodgeDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, Florida.
Lauren A DalvinDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota; and.ORCID 0000-0001-9710-4284

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Lila J. Rutten · 1985 to 2026
$151.3M
Institutional Career Development CoreKL2TR002379 · NCATS · MAYO CLINIC ROCHESTER · PI NILUFER ERTEKIN-TANER · 2017 to 2026
$14.9M
NCATS NIH HHS KL2 TR002379NCI NIH HHS P30 CA015083
6 · The paper itself

Abstract

purposeTo identify demographic and clinical factors associated with delayed diagnosis in patients with primary vitreoretinal lymphoma (VRL).

methodsRetrospective, tertiary referral center-based cohort study of all patients at Mayo Clinic in Rochester, Minnesota, with a biopsy-proven diagnosis of VRL from January 1, 2000, to October 31, 2022.

resultsThere were 87 patients included during the 22-year study period with 73 patients (83.9%) diagnosed with VRL upon initial evaluation at the tertiary center, with the other 14 patients (16.1%) diagnosed later. The median referral time was 4.8 months (range: 0-113 months). Patients who received an initial diagnosis of inflammatory uveitis or another incorrect diagnosis elsewhere were referred slower than those initially diagnosed with VRL (P = 0.04). The most common incorrect initial diagnosis from an outside institution was inflammatory uveitis (n = 35, 40.2%). When patients were split into four groups based on referral time, prior use of corticosteroids was associated with a significant delay in referral (P = 0.03).

conclusionDiagnosing VRL continues to be challenging, as months-long delays from initial evaluation to expert referral center evaluation are common. Prior use of corticosteroids was associated with delay in diagnosis and referral time, underscoring the need to increase awareness regarding differences between VRL and uveitis.

Indexed as

Delayed DiagnosisRetinal NeoplasmsVitreous BodyAdultAgedAged, 80 and overFemaleHumansIntraocular LymphomaMaleMiddle AgedReferral and ConsultationRetrospective Studies

Identifiers

PMID39287543
PMCPMC13314028

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.