Evidence map›Paper›PMID 39287506›Full record

ArticleAndrology2025

Genital gender-affirming surgery trends in Germany: Total population data with 19,600 cases from 2006 to 2022.

Cem Aksoy, Sascha Wellenbrock, Philipp Reimold, Philipp Karschuck, Mahmut Ozturk, Tobias Hirsch, Michael Sohn, Nicole Eisenmenger, Sabine Kliesch, Saskia Morgenstern and 3 more

Abstract read
In one paragraph

Article in Andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cem AksoyDepartment of Urology, Philipps-University Marburg, Marburg, Germany.ORCID 0000-0002-0875-5120
Sascha WellenbrockDepartment of Plastic Surgery, Center for Transgender Health, University Hospital Münster, Münster, Germany.
Philipp ReimoldDepartment of Urology, Philipps-University Marburg, Marburg, Germany.
Philipp KarschuckDepartment of Urology, Philipps-University Marburg, Marburg, Germany.
Mahmut OzturkDepartment of Plastic Surgery, Center for Transgender Health, University Hospital Münster, Münster, Germany.
Tobias HirschDepartment of Plastic Surgery, Center for Transgender Health, University Hospital Münster, Münster, Germany.
Michael SohnDepartment of Urology, AGAPLESION Markus-Hospital, Frankfurt, Germany.
Nicole EisenmengerReimbursement Institute, Hürth, Germany.
Sabine KlieschCenter for Reproductive Medicine and Andrology/Clinical and Surgical Andrology, Center for Transgender Health, University Hospital Münster, Münster, Germany.
Saskia MorgensternDepartment of Urology, AGAPLESION Markus-Hospital, Frankfurt, Germany.
Aristeidis ZacharisDepartment of Urology, Philipps-University Marburg, Marburg, Germany.
Johannes HuberDepartment of Urology, Philipps-University Marburg, Marburg, Germany.
Luka FlegarDepartment of Urology, Philipps-University Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo delineate the current trends regarding gender-affirming surgeries (GAS) in Germany.

methodsAnalysis of German hospital quality reports from 2006 to 2022 was conducted using the reimbursement.info tool. The German procedure classification (OPS) codes 5-646.0 for masculinizing- and 5-646.1 for feminizing surgery were assessed to identify GAS. Linear regression models were utilized for the analysis and depiction of current trends.

resultsA total of 19,632 gender-affirming procedures were performed during the study period with an exponential increase over the years. Masculinizing surgeries increased from 246 in 2006 to 1291 cases in 2022 (increase by 424%; p < 0.001). The highest annual increase of 37.2% in numbers was from 2018 to 2019 (from 1235 to 1694 cases). Feminizing surgeries increased from 180 cases in 2006 to 799 procedures in 2022 (increase by 343%; p < 0.001). The cases increased most between 2015 and 2016 from 277 to 502 cases (81.2%). The number of hospitals offering these surgeries expanded from 24 in 2006 to 29 in 2022 (21% increase; p < 0.001).

conclusionThis study demonstrates an exponential growth in numbers feminizing and masculinizing of GAS performed each year in Germany. Furthermore, a discernible trend emerges with a propensity for concentration of procedures within selected high-caseload centers across Germany.

Indexed as

Gender-Affirming SurgeryAdolescentAdultAgedFemaleGermanyHumansMaleMiddle AgedYoung Adultgender‐affirming surgeryhealth services researchpopulation‐based studytransgendertreatment trends

Identifiers

PMID39287506
PMCPMC12368935

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.