Evidence map›Paper›PMID 39287432›Full record

ReviewJournal of bacteriology2024

Regulation of bacterial virulence genes by PecS family transcription factors.

George C Nwokocha, Arpita Ghosh, Anne Grove

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. TheJournal of bacteriology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

George C NwokochaCorteva Agriscience, Johnston, Iowa, USA.
Arpita GhoshDepartment of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana, USA.
Anne GroveDepartment of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana, USA.ORCID 0000-0002-4390-0354

Funding

National Science Foundation (NSF) MCB-2153410
6 · The paper itself

Abstract

Bacterial plant pathogens adjust their gene expression programs in response to environmental signals and host-derived compounds. This ensures that virulence genes or genes encoding proteins, which promote bacterial fitness in a host environment, are expressed only when needed. Such regulation is in the purview of transcription factors, many of which belong to the ubiquitous multiple antibiotic resistance regulator (MarR) protein family. PecS proteins constitute a subset of this large protein family. PecS has likely been distributed by horizontal gene transfer, along with the divergently encoded efflux pump PecM, suggesting its integration into existing gene regulatory networks. Here, we discuss the roles of PecS in the regulation of genes associated with virulence and fitness of bacterial plant pathogens. A comparison of phenotypes and differential gene expression associated with the disruption of

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialTranscription FactorsVirulenceVirulence FactorsBacterial ProteinsTranscription FactorsVirulence Factorsbacterial fitnessMarRPecMplant pathogenvirulence

Identifiers

PMID39287432
PMCPMC11500572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.