Evidence map›Paper›PMID 39287378›Full record

ArticlemSystems2024

Evolution of ceftazidime-avibactam resistance driven by mutations in double-copy

Xiaofan Zhang, Yinrong Xie, Ying Zhang, Tailong Lei, Longjie Zhou, Jiayao Yao, Lin Liu, Haiyang Liu, Jintao He, Yunsong Yu and 2 more

Abstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Carbapenem-resistantMicrobiology spectrum · 2025
    Article
  10. Emergence and evolution of rare ST592Frontiers in cellular and infection microbiology · 2025
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaofan Zhang *Centre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yinrong Xie *Department of Clinical Laboratory, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, Fujian, China.
Ying Zhang *Centre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Tailong LeiDepartment of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID 0000-0003-2067-1787
Longjie ZhouCentre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Jiayao YaoCentre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Lin LiuDepartment of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Haiyang LiuCentre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Jintao HeCentre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yunsong YuCenter for General Practice Medicine, Department of Infectious Diseases, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID 0000-0003-2903-918X
Yuexing TuCentre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID 0000-0003-3073-8746
Xi LiCentre of Laboratory Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID 0000-0002-8838-7814

Funding

MOST | National Natural Science Foundation of China (NSFC) 82472323, 82172306Research and Development Program of China Province 2023C03068Zhejiang Provincial Public Projects LGD21H190001
6 · The paper itself

Abstract

IMPORTANCE: To date, ceftazidime-avibactam (CZA) resistance caused by double-copy

Indexed as

Azabicyclo CompoundsBacterial Proteinsbeta-LactamasesCeftazidimeDrug CombinationsKlebsiella InfectionsKlebsiella pneumoniaeMutationAnti-Bacterial AgentsCarbapenem-Resistant EnterobacteriaceaeCarbapenemsDrug Resistance, Multiple, BacterialEvolution, MolecularHumansMicrobial Sensitivity TestsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsCeftazidimeDrug CombinationsblaKPC-189CRKPCZA resistancedouble-copyST11

Identifiers

PMID39287378
PMCPMC11495026

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.