Evidence map›Paper›PMID 39287149›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Highly Efficient Synergistic Chemotherapy and Magnetic Resonance Imaging for Targeted Ovarian Cancer Therapy Using Hyaluronic Acid-Coated Coordination Polymer Nanoparticles.

Guang Li, Shengying Shi, Jingxiu Tan, Lijuan He, Qiwen Liu, Feng Fang, Huijiao Fu, Min Zhong, Ziyi Mai, Rui Sun and 5 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
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  11. Review
  12. Polymer Nanoparticles Advancements for Gynecological Cancers.International journal of nanomedicine · 2025
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Guang LiDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Shengying ShiDepartment of Nursing, Nanfang Hospital, Southern Medical University, Guangzhou, 510000, China.
Jingxiu TanDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Lijuan HeDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Qiwen LiuDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Feng FangDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Huijiao FuDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Min ZhongDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Ziyi MaiDepartment of Pharmacy, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, China.
Rui SunDepartment of Laboratory Medicine, Dongguan Institute of Clinical Cancer Research, Affiliated Dongguan Hospital, Southern Medical University, Dongguan, 523018, China.
Kun LiuSchool of Pharmacy, Guangdong Medical University, Dongguan, 523808, China.
Zhenzhen FengDepartment of Laboratory Medicine, Dongguan Institute of Clinical Cancer Research, Affiliated Dongguan Hospital, Southern Medical University, Dongguan, 523018, China.
Peiqin LiangDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.
Zhiqiang YuDepartment of Laboratory Medicine, Dongguan Institute of Clinical Cancer Research, Affiliated Dongguan Hospital, Southern Medical University, Dongguan, 523018, China.ORCID 0000-0002-1688-5558
Xuefeng WangDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, 510630, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2114050001718Innovation Platform and Talent Program of Hunan Province, China 2021SK4021Red de Salud Materno Infantil y del Desarrollo 2023RX31Third Affiliated Hospital of Southern Medical University Presidential Foundation YM202202
6 · The paper itself

Abstract

The diagnosis and treatment of ovarian cancer (OC) are still a grand challenge, more than 70% of patients are diagnosed at an advanced stage with a dismal prognosis. Magnetic resonance imaging (MRI) has shown superior results to other examinations in preoperative assessment, while cisplatin-based chemotherapy is the first-line treatment for OC. However, few previous studies have brought together the two rapidly expanding fields. Here a technique is presented using cisplatin prodrug (Pt-COOH), Fe

Indexed as

Antineoplastic AgentsCisplatinHyaluronic AcidMagnetic Resonance ImagingNanoparticlesOvarian NeoplasmsPolymersAnimalsCell Line, TumorDisease Models, AnimalFemaleGossypolHumansMiceAntineoplastic AgentsCisplatinGossypolHyaluronic AcidPolymersferroptosisgsh depletionintegrated diagnosis and treatmentnuclear magnetic resonance imaging (MRI)ovarian cancer (OC)

Identifiers

PMID39287149
PMCPMC11538696

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.