ArticleCirculation2024
Worldwide CTEPH Registry: Long-Term Outcomes With Pulmonary Endarterectomy, Balloon Pulmonary Angioplasty, and Medical Therapy.
Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02656238 (New International CTEPH Database), which is not on this map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
New International CTEPH Database
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The volume-outcome relationship for pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension.The European respiratory journal · 2025Pooled it
- Right Ventricular-Pulmonary Arterial Coupling by Serial TAPSE/sPAP: A Noninvasive Predictor for Clinical Outcomes in Chronic Thromboembolic Pulmonary Hypertension.Pulmonary circulation · 2026Article
- Comparison of Clinical, Hemodynamic and Imaging Profiles Between Isolated Pulmonary Vasculitis and Chronic Thromboembolic Pulmonary Hypertension.Pulmonary circulation · 2026Article
- The Impact of Balloon Pulmonary Angioplasty (BPA) on Changes in the Liver Fibrosis Index (FIB-4 Index) in Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH).Journal of clinical medicine · 2026Article
- Multimodal Management of Chronic Thromboembolic Pulmonary Hypertension: A Narrative Review of Treatment Selection and Sequencing.Journal of cardiovascular development and disease · 2026Review
- Retrograde Balloon Pulmonary Angioplasty for Otherwise Uncrossable Lesions in Chronic Thromboembolic Pulmonary Hypertension.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Multimodality Imaging of Pulmonary Artery Aneurysm in Chronic Thromboembolic Pulmonary Hypertension.JACC. Case reports · 2026Article
- Significance of diffusing capacity of the lungs for carbon monoxide on chronic thromboembolic pulmonary hypertension.Thorax · 2026Article
- Article
- Safety and Feasibility of Same-Day Discharge After Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: A Single-Center Retrospective Study.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Long-Term Survival of Balloon Pulmonary Angioplasty for Inoperable Chronic Thromboembolic Pulmonary Hypertension: A Multicenter Study.JACC. Asia · 2026Article
- Predictors of long-term survival after pulmonary endarterectomy.JTCVS open · 2026Article
- RAP/PAWP Following CTEPH Surgery: A Simple Ratio for Complex Risk.Respirology (Carlton, Vic.) · 2026Article
- Balloon Pulmonary Angioplasty for CTEPH: Emerging Evidence From China: Better Done Than Deferred.JACC. Asia · 2026Article
- Clinical Outcomes of Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension: A Retrospective Cohort Study From a Latin American Care Center.Pulmonary circulation · 2026Article
- Invasive Management for Acute-on-Chronic Thromboembolic Pulmonary Hypertension: Feasibility and Clinical Outcomes in a Single-Center Cohort.Pulmonary circulation · 2026Article
- Lung Injury After Balloon Pulmonary Angioplasty for CTEPH: Histopathologic Findings and Management Implications.Pulmonary circulation · 2026Article
- The Role of Medical Therapy Before and After Balloon Pulmonary Angioplasty: CTEPH AC Registry Across Japan.Pulmonary circulation · 2026Article
- Observational
- Rescue Balloon Pulmonary Angioplasty Prior to Pulmonary Endarterectomy With Concomitant Mitral Valve Plasty in High-Risk Operable CTEPH.Pulmonary circulation · 2026Article
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe European Chronic Thromboembolic Pulmonary Hypertension (CTEPH) registry, conducted between 2007 and 2012, reported the major impact of pulmonary endarterectomy (PEA) on the long-term survival of patients with CTEPH. Since then, 2 additional treatments for inoperable CTEPH have become available: balloon pulmonary angioplasty (BPA), and an approved oral drug therapy with the guanylate cyclase stimulator riociguat. The current registry aimed to evaluate the effect of these new therapeutic approaches in a worldwide context.
methodsParticipation in this international global registry included 34 centers in 20 countries. Between February 2015 and September 2016, 1009 newly diagnosed, consecutive patients were included and followed until September 2019.
resultsOverall, 605 patients (60%) underwent PEA and 185 (18%) underwent BPA; 76% of the 219 remaining patients not receiving mechanical intervention (ie, neither PEA nor BPA) were treated with pulmonary hypertension drugs. Of patients undergoing PEA and BPA, 38% and 78% also received drugs for pulmonary hypertension, respectively. Median age at diagnosis was higher in the BPA and No PEA/BPA groups than in the PEA group: 66 and 69, respectively, versus 60 years. Pulmonary vascular resistance (PVR) was similar in all groups, with an average of 643 dynes.s.cm
conclusionsThis second international CTEPH registry reveals important improvement in patient survival since the introduction of BPA and an approved drug for pulmonary hypertension. The type of anticoagulation regimen did not influence survival. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02656238.
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