Evidence map›Paper›PMID 39286649›Full record

ArticleJournal of translational autoimmunity2024

Vascular injury derived apoptotic exosome-like vesicles trigger autoimmunity.

Sandrine Juillard, Annie Karakeussian-Rimbaud, Marie-Hélène Normand, Julie Turgeon, Charlotte Veilleux-Trinh, Alexa C Robitaille, Joyce Rauch, Andrzej Chruscinski, Nathalie Grandvaux, Éric Boilard and 2 more

Abstract read
In one paragraph

Article in Journal of translational autoimmunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Apoptotic extracellular vesicles: unveiling mechanisms, diverse functions, and biomedical implications.Apoptosis : an international journal on programmed cell death · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sandrine JuillardCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Annie Karakeussian-RimbaudCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Marie-Hélène NormandCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Julie TurgeonCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Charlotte Veilleux-TrinhCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Alexa C RobitailleCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Joyce RauchDivision of Rheumatology, Research Institute of the McGill University Health Centre (RI MUHC), 1001 Bd Décarie, Montréal, QC, H4A 3J1, Canada.
Andrzej ChruscinskiUniversity of Toronto, 27 King's College Cir, Toronto, ON, M5S 1A1, Canada.
Nathalie GrandvauxCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Éric BoilardCentre de Recherche Du CHU de Québec, Université Laval, 2705 Bd Laurier, Québec, QC, G1V 4G2, Canada.
Marie-Josée HébertCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.
Mélanie DieudéCentre de Recherche Du Centre Hospitalier de l'Université de Montréal (CRCHUM), Tour Viger, R12.218, 900 Rue St-Denis, Montréal, QC, H2X 0A9, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to a central tenet of classical immune theory, a healthy immune system must avoid self-reactive lymphocyte clones but we now know that B cells repertoire exhibit some level of autoreactivity. These autoreactive B cells are thought to rely on self-ligands for their clonal selection and survival. Here, we confirm that healthy mice exhibit self-reactive B cell clones that can be stimulated

Indexed as

Anti-LG3ApoExosAutoantibodiesSystemic lupus erythematosus (SLE)Toll-like receptors (TLR)

Identifiers

PMID39286649
PMCPMC11402544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.